Progress in research of histone methyltransferases and their inhibitors in cancer treatment
文献类型：期刊论文
| 作者 | Zhang Jie; Ding Jian ; Chen Yi
|
| 刊名 | Chinese Journal New Drugs
 |
| 出版日期 | 2014 |
| 卷号 | 23期号:5页码:533-540 |
| 关键词 | histone methylation modification histone methyltransferases (HMTs) anti-cancer drug epigenetics |
| ISSN号 | 1003-3734 |
| 其他题名 | 组蛋白甲基转移酶及其相应抑制剂在抗肿瘤领域的研究进展 |
| 文献子类 | Review |
| 英文摘要 | Aberrant histone methylation regulated by abnormal histone methyltransferases (HMTs) has emerged as a critical player in the onset and progression of cancer in numerous tumor types. The reversal of aberrant histone methylation changes has therefore emerged as a potential strategy for the treatment of cancer. A number of compounds targeting these HMTs have been developed as novel therapies, in which some are in clinical trials. This review highlights the roles of some HMTs in tumorigenesis and emerging therapies being developed for the treatment of cancer. |
| 资助项目 | 国家自然科学基金[00000000] |
| WOS研究方向 | Pharmacology & Pharmacy (provided by Clarivate Analytics) |
| 语种 | 中文 |
| CSCD记录号 | CSCD:5101346 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/269344]  |
| 专题 | 药理学第一研究室 |
| 作者单位 | Division of Antitumor Pharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China. |
| 推荐引用方式 GB/T 7714 | Zhang Jie,Ding Jian,Chen Yi. Progress in research of histone methyltransferases and their inhibitors in cancer treatment[J]. Chinese Journal New Drugs,2014,23(5):533-540. |
| APA | Zhang Jie,Ding Jian,&Chen Yi.(2014).Progress in research of histone methyltransferases and their inhibitors in cancer treatment.Chinese Journal New Drugs,23(5),533-540. |
| MLA | Zhang Jie,et al."Progress in research of histone methyltransferases and their inhibitors in cancer treatment".Chinese Journal New Drugs 23.5(2014):533-540. |
入库方式： OAI收割
来源：上海药物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。