中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页 机构 成果 学者
  
  1. CAS IR Grid
  2. 上海药物研究所
  3. 中国科学院上海药物研究所
  4. 药理学第一研究室
Bacillus as a potential diagnostic marker for yellow tongue coating

文献类型：期刊论文

作者Ye, Juan1,5; Cai, Xueting1,5; Yang, Jie1,5; Sun, Xiaoyan1,5; Hu, Chunping1,5; Xia, Junquan1,5; Shen, Jianping1,5; Su, Kelei1,5; Yan, Huaijiang1,5; Xu, Yuehua5
刊名SCIENTIFIC REPORTS
出版日期2016-08-31
卷号6
ISSN号2045-2322
DOI10.1038/srep32496
文献子类Article
英文摘要Observation of tongue coating, a foundation for clinical diagnosis and treatment in traditional Chinese medicine (TCM), is a major indicator of the occurrence, development, and prognosis of disease. The biological basis of tongue diagnosis and relationship between the types and microorganisms of tongue coating remain elusive. Thirteen chronic erosive gastritis (CEG) patients with typical yellow tongue coating (YTC) and ten healthy volunteers with thin white tongue coating (WTC) were included in this study. Patients were provided a 2-course targeted treatment of a herbal medicine Ban Xia Xie Xin decoction, traditionally prescribed for CEG patients with YTC, to evaluate the relationship between tongue coating microbiota and diagnosis of CEG with typical YTC. The tongue coating segregation structure was determined using Illumina Miseq sequencing of the V4-V5 region of the 16S ribosomal RNA gene. Bacillus was significantly observed only in CEG patients with YTC, but not in patients who received the decoction. YTC (n = 22) and WTC (n = 29) samples were collected for bacterial culturing to illustrate the relationship between Bacillus and YTC. The Bacillus positivity rate of YTC samples was 72.7%; Bacillus was not observed in WTC samples. In conclusion, Bacillus was strongly associated with YTC.
WOS关键词PANCREATIC-CANCER ; ORAL-CAVITY ; MICROBIOME ; GASTRITIS ; CHINA
资助项目Jiangsu Province Funds for Distinguished Young Scientists[BK20140049] ; China Postdoctoral Science Foundation[2015M580186] ; National Basic Research Program of China (973 Program)[2014CB542903]
WOS研究方向Science & Technology - Other Topics
语种英语
WOS记录号WOS:000382246600001
出版者NATURE PUBLISHING GROUP
源URL[http://119.78.100.183/handle/2S10ELR8/275921]  
专题药理学第一研究室
通讯作者Hu, Jingqing; Cao, Peng
作者单位1.Nanjing Univ Chinese Med, Affiliated Hosp Integrated Tradit Chinese & Weste, Nanjing 210028, Jiangsu, Peoples R China;
2.Mem Sloan Kettering Canc Ctr, Dept Med, New York, NY 10065 USA;
3.Chinese Acad Sci, Shanghai Inst Mat Med, Dept Pharmacol, Shanghai 201203, Peoples R China;
4.China Acad Chinese Med Sci, Inst Basic Theory Tradit Chinese Med, Beijing 100700, Peoples R China
5.Jiangsu Prov Acad Tradit Chinese Med, Lab Cellular & Mol Biol, Nanjing 210028, Jiangsu, Peoples R China;
推荐引用方式
GB/T 7714		 Ye, Juan,Cai, Xueting,Yang, Jie,et al. Bacillus as a potential diagnostic marker for yellow tongue coating[J]. SCIENTIFIC REPORTS,2016,6.
APA Ye, Juan.,Cai, Xueting.,Yang, Jie.,Sun, Xiaoyan.,Hu, Chunping.,...&Cao, Peng.(2016).Bacillus as a potential diagnostic marker for yellow tongue coating.SCIENTIFIC REPORTS,6.
MLA Ye, Juan,et al."Bacillus as a potential diagnostic marker for yellow tongue coating".SCIENTIFIC REPORTS 6(2016).

入库方式： OAI收割

来源：上海药物研究所

浏览0
下载0
收藏0
其他版本

除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。