FeCl3-catalyzed selective acylation of amines with 1,3-diketones via C-C bond cleavage
文献类型：期刊论文
| 作者 | Wang, Sinan2,3,5; Yu, Yang2,3; Chen, Xuyun2,3; Zhu, Haipan1; Du, Peile1; Liu, Guohua1; Lou, Liguang5 ; Li, Hao2,3; Wang, Wei2,3,4
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| 刊名 | TETRAHEDRON LETTERS
 |
| 出版日期 | 2015-06-03 |
| 卷号 | 56期号:23页码:3093-3096 |
| 关键词 | FeCl3 Acylation 1,3-Diketones C-C bond cleavage |
| ISSN号 | 0040-4039 |
| DOI | 10.1016/j.tetlet.2014.12.146 |
| 文献子类 | Article |
| 英文摘要 | We describe a novel FeCl3 catalyzed selective acylation of amines involving the C-C bond cleavage of simple 1,3-diketones. The process proceeds efficiently under a neat condition to give structurally diverse amides. Notably, the acylation process displays high selectivity toward amines over hydroxyl functionality. Traditionally difficult aromatic amines and sterically demanding disubstituted amines can engage in the process with high efficiency. (C) 2015 Elsevier Ltd. All rights reserved. |
| WOS关键词 | STAUDINGER LIGATION ; AMIDE SYNTHESIS ; OXIDATIVE AMIDATION ; PEPTIDE-SYNTHESIS ; CARBOXYLIC-ACIDS ; CARBON ; ACTIVATION ; CHEMISTRY ; ALDEHYDES ; CYCLOPROPANES |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000356544800028 |
| 出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/276497]  |
| 专题 | 药理学第一研究室 |
| 通讯作者 | Li, Hao |
| 作者单位 | 1.Shanghai Normal Univ, Minist Educ, Key Lab Resource Chem, Shanghai 200234, Peoples R China; 2.E China Univ Sci & Technol, Sch Pharm, Shanghai Key Lab New Drug Design, Shanghai 200237, Peoples R China; 3.E China Univ Sci & Technol, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China; 4.Univ New Mexico, Dept Chem & Chem Biol, Albuquerque, NM 87131 USA 5.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China; |
| 推荐引用方式 GB/T 7714 | Wang, Sinan,Yu, Yang,Chen, Xuyun,et al. FeCl3-catalyzed selective acylation of amines with 1,3-diketones via C-C bond cleavage[J]. TETRAHEDRON LETTERS,2015,56(23):3093-3096. |
| APA | Wang, Sinan.,Yu, Yang.,Chen, Xuyun.,Zhu, Haipan.,Du, Peile.,...&Wang, Wei.(2015).FeCl3-catalyzed selective acylation of amines with 1,3-diketones via C-C bond cleavage.TETRAHEDRON LETTERS,56(23),3093-3096. |
| MLA | Wang, Sinan,et al."FeCl3-catalyzed selective acylation of amines with 1,3-diketones via C-C bond cleavage".TETRAHEDRON LETTERS 56.23(2015):3093-3096. |
入库方式： OAI收割
来源：上海药物研究所
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