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Apoptosis, autophagy, necroptosis, and cancer metastasis
文献类型：期刊论文
| 作者 | Su, Zhenyi2,3; Yang, Zuozhang4,5; Xu, Yongqing5; Chen, Yongbin1; Yu, Qiang6
|
| 刊名 | MOLECULAR CANCER
 |
| 出版日期 | 2015-02-21 |
| 卷号 | 14 |
| 关键词 | Apoptosis Autophagy Necroptosis Metastasis |
| ISSN号 | 1476-4598 |
| DOI | 10.1186/s12943-015-0321-5 |
| 文献子类 | Review |
| 英文摘要 | Metastasis is a crucial hallmark of cancer progression, which involves numerous factors including the degradation of the extracellular matrix (ECM), the epithelial-to-mesenchymal transition (EMT), tumor angiogenesis, the development of an inflammatory tumor microenvironment, and defects in programmed cell death. Programmed cell death, such as apoptosis, autophagy, and necroptosis, plays crucial roles in metastatic processes. Malignant tumor cells must overcome these various forms of cell death to metastasize. This review summarizes the recent advances in the understanding of the mechanisms by which key regulators of apoptosis, autophagy, and necroptosis participate in cancer metastasis and discusses the crosstalk between apoptosis, autophagy, and necroptosis involved in the regulation of cancer metastasis. |
| WOS关键词 | CELL LUNG-CANCER ; LYMPH-NODE METASTASIS ; HUMAN PROSTATE-CANCER ; PROGRAMMED NECROSIS ; ANOIKIS RESISTANCE ; TUMOR-METASTASIS ; DRUG-RESISTANCE ; KAPPA-B ; PI3K/AKT/MTOR PATHWAY ; CLINICAL-SIGNIFICANCE |
| 资助项目 | National Natural Science Foundation of China[81460440] ; National Natural Science Foundation of China[31300666] ; National Natural Science Foundation of China[81260322] ; National Natural Science Foundation of China[81372322] ; first Class General Financial Grant from the China Postdoctoral Science Foundation[2013M542478] ; Natural Science Foundation of Yunnan Province[2012FB163] ; Joint Special Funds for the Department of Science and Technology of Yunnan Province-Kunming Medical University[2014FB059] ; Specialty Fund of High-level Talents Medical Personnel Training of Yunnan Province[D-201242] |
| WOS研究方向 | Biochemistry & Molecular Biology ; Oncology |
| 语种 | 英语 |
| WOS记录号 | WOS:000350509500001 |
| 出版者 | BIOMED CENTRAL LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/276633]  |
| 专题 | 药理学第一研究室 |
| 通讯作者 | Yang, Zuozhang |
| 作者单位 | 1.Chinese Acad Sci, Key Lab Anim Models & Human Dis Mech, Kunming Inst Zool, Kunming 650223, Yunnan, Peoples R China; 2.Southeast Univ, Sch Med, Dept Biochem & Mol Biol, Nanjing 210009, Jiangsu, Peoples R China; 3.Harvard Univ, Sch Med, Dept Cell Biol, Boston, MA 02115 USA; 4.Kunming Med Univ, Affiliated Hosp 3, Tumor Hosp Yunnan Prov, Dept Orthopaed,Bone & Soft Tissue Tumors Res Ctr, Kunming 650118, Yunnan, Peoples R China; 5.Kunming Gen Hosp Chengdu Mil Command, Dept Orthoped, Kunming 650118, Yunnan, Peoples R China; 6.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Su, Zhenyi,Yang, Zuozhang,Xu, Yongqing,et al. Apoptosis, autophagy, necroptosis, and cancer metastasis[J]. MOLECULAR CANCER,2015,14. |
| APA | Su, Zhenyi,Yang, Zuozhang,Xu, Yongqing,Chen, Yongbin,&Yu, Qiang.(2015).Apoptosis, autophagy, necroptosis, and cancer metastasis.MOLECULAR CANCER,14. |
| MLA | Su, Zhenyi,et al."Apoptosis, autophagy, necroptosis, and cancer metastasis".MOLECULAR CANCER 14(2015). |
入库方式： OAI收割
来源：上海药物研究所
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