3-Hydroxycarboplatin, a Simple Carboplatin Derivative Endowed with an Improved Toxicological Profile
文献类型：期刊论文
| 作者 | Liu, Weiping1; Chen, Xizhu1; Ye, Qingsong1; Hou, Shuqian1; Lou, Liguang2 ; Xie, Chengying2
|
| 刊名 | PLATINUM METALS REVIEW
 |
| 出版日期 | 2012-10 |
| 卷号 | 56期号:4页码:248-256 |
| ISSN号 | 0032-1400 |
| DOI | 10.1595/147106712X654204 |
| 文献子类 | Article |
| 英文摘要 | 3-Hydroxycarboplatin, a simple carboplatin derivative, was synthesised using a novel method, characterised and evaluated for its anticancer activity in vitro and in vivo. It shows comparable antitumour activity to that of carboplatin but has much lower toxicity particularly with respect to myelosuppression, revealing great potential for development as a new antitumour platinum drug to replace carboplatin. |
| WOS关键词 | PLATINUM(II) COMPLEXES ; SALICYLATE DERIVATIVES ; ANTICANCER ACTIVITY ; ANTITUMOR-ACTIVITY ; CANCER ; ANALOG |
| 资助项目 | National Science Foundation of P. R. China[21161010] ; China National Research and Development (RD) Program[2012BAE06B08] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000313558800006 |
| 出版者 | JOHNSON MATTHEY PUBL LTD CO |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/277914]  |
| 专题 | 药理学第一研究室 |
| 通讯作者 | Liu, Weiping |
| 作者单位 | 1.Kunming Inst Precious Met, State Key Lab Adv Technol Comprehens Utilizat Pla, Kunming 650106, Yunnan, Peoples R China; 2.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liu, Weiping,Chen, Xizhu,Ye, Qingsong,et al. 3-Hydroxycarboplatin, a Simple Carboplatin Derivative Endowed with an Improved Toxicological Profile[J]. PLATINUM METALS REVIEW,2012,56(4):248-256. |
| APA | Liu, Weiping,Chen, Xizhu,Ye, Qingsong,Hou, Shuqian,Lou, Liguang,&Xie, Chengying.(2012).3-Hydroxycarboplatin, a Simple Carboplatin Derivative Endowed with an Improved Toxicological Profile.PLATINUM METALS REVIEW,56(4),248-256. |
| MLA | Liu, Weiping,et al."3-Hydroxycarboplatin, a Simple Carboplatin Derivative Endowed with an Improved Toxicological Profile".PLATINUM METALS REVIEW 56.4(2012):248-256. |
入库方式： OAI收割
来源：上海药物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。