Chemical structure and immunoinhibitory activity of a pectic polysaccharide containing glucuronic acid from the leaves of Diospyros kaki
文献类型：期刊论文
| 作者 | Duan, Jinyou1,2,3; Chen, Vincent L.2,3; Dong, Qun1; Ding, Kan1 ; Fang, Jinian1
|
| 刊名 | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
 |
| 出版日期 | 2010-06-01 |
| 卷号 | 46期号:5页码:465-470 |
| 关键词 | Pectin Rhamnogalacturonan Immunological activity Diospyros kaki |
| ISSN号 | 0141-8130 |
| DOI | 10.1016/j.ijbiomac.2010.03.014 |
| 文献子类 | Article |
| 英文摘要 | Pectin is a family of complex polysaccharides characterized by the presence of 1,4-linked alpha-galacturonic acid residues in the backbone and is more recognized for its potential bioactive properties. Herein we reported the structural and biological features of a pectic fraction DL-4OAC-1 from the leaves of Diospyros kaki. Chemical and spectral analysis revealed this polysaccharide possessed a backbone composed of a repeating disaccharide [-> 4)-alpha-GalAp-(1 -> 2)-alpha-Rhap-(1 ->], substituted at some O-4 of Rhap residues and O-3 of GalAp residues by the side chains consisting of Araf, Galp, Xylp, and in particular terminal GlcAp residues. The immunological assay in vitro showed that this distinct pectic fraction could inhibit the LPS-induced B lymphocyte proliferation and had no effect on the ConA-induced T lymphocyte proliferation. (C) 2010 Elsevier B.V. All rights reserved. |
| WOS关键词 | RHAMNOGALACTURONAN-I ; ARABINOGALACTAN ; FEATURES ; HETEROXYLAN ; METHYLATION ; DEGRADATION ; PROTEINS ; ASSAY |
| WOS研究方向 | Biochemistry & Molecular Biology ; Chemistry ; Polymer Science |
| 语种 | 英语 |
| WOS记录号 | WOS:000278586200001 |
| 出版者 | ELSEVIER SCIENCE BV |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/278887]  |
| 专题 | 药理学第三研究室 |
| 通讯作者 | Duan, Jinyou |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai Inst Biol Sci, Shanghai 201203, Peoples R China; 2.Harvard Univ, Sch Med, Boston, MA 02115 USA 3.Brigham & Womens Hosp, Channing Lab, Boston, MA 02115 USA; |
| 推荐引用方式 GB/T 7714 | Duan, Jinyou,Chen, Vincent L.,Dong, Qun,et al. Chemical structure and immunoinhibitory activity of a pectic polysaccharide containing glucuronic acid from the leaves of Diospyros kaki[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2010,46(5):465-470. |
| APA | Duan, Jinyou,Chen, Vincent L.,Dong, Qun,Ding, Kan,&Fang, Jinian.(2010).Chemical structure and immunoinhibitory activity of a pectic polysaccharide containing glucuronic acid from the leaves of Diospyros kaki.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,46(5),465-470. |
| MLA | Duan, Jinyou,et al."Chemical structure and immunoinhibitory activity of a pectic polysaccharide containing glucuronic acid from the leaves of Diospyros kaki".INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 46.5(2010):465-470. |
入库方式： OAI收割
来源：上海药物研究所
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