Kadcoccilactones K-R, triterpenoids from Kadsura coccinea
文献类型：期刊论文
| 作者 | Gao, Xue-Mei1; Pu, Jian-Xin1; Xiao, Wei-Lie1; Huang, Sheng-Xiong1; Lou, Li-Guang2 ; Sun, Han-Dong1
|
| 刊名 | TETRAHEDRON
 |
| 出版日期 | 2008-12-15 |
| 卷号 | 64期号:51页码:11673-11679 |
| ISSN号 | 0040-4020 |
| 关键词 | Kadsura coccinea Triterpenoid Kadcoccilactone |
| DOI | 10.1016/j.tet.2008.10.011 |
| 文献子类 | Article |
| 英文摘要 | Phytochemical investigation on the stems of Kadsuru coccinea led to the isolation of 8 new triterpenoids, kadcoccilactones K-R (1-8), and 10 known analogues. Their Structures were elucidated on the basis of extensive spectroscopic analysis. Compounds 1-3 characterized with an aromatic ring E in their molecules are rarely naturally Occurred kadlongilactone derivatives. Moreover, all compounds were evaluated for their inhibitory activity against K562, Bel-7402, and A549 human tumor cells. Compounds 9 and 10 exhibited potent cytotoxicity against K562, Bel-7402, and A549 cell lines with IC50 Values less than 0.1, 0.1, and 1.0 mu m, respectively. (C) 2008 Elsevier Ltd. All rights reserved. |
| WOS关键词 | UNIQUE SKELETON ; LIGNANS ; LONGIPEDUNCULATA ; DILACTONES ; PHILIPPINENSIS ; HETEROCLITA ; INTERIOR |
| 资助项目 | Natural Science Foundation of China[30830115] ; Natural Science Foundation of China[20802082] ; Yunnan Province[20061300420] ; Yunnan Province[2005XY04] ; Yunnan Province[2007BC004] ; Yong Academic and Technical Leader Raising Foundation of Yunnan Province[2006PY01] ; Chinese Academy of Sciences[00000000] ; Western Doctoral Foundation of Chinese Academy of Sciences[00000000] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| 出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
| WOS记录号 | WOS:000261714100018 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/279409]  |
| 专题 | 药理学第一研究室 |
| 通讯作者 | Xiao, Wei-Lie |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China; 2.Chinese Acad Sci, Shanghai Inst Biol Sci, Shanghai Inst Mat Med, Shanghai 200032, Peoples R China |
| 推荐引用方式 GB/T 7714 | Gao, Xue-Mei,Pu, Jian-Xin,Xiao, Wei-Lie,et al. Kadcoccilactones K-R, triterpenoids from Kadsura coccinea[J]. TETRAHEDRON,2008,64(51):11673-11679. |
| APA | Gao, Xue-Mei,Pu, Jian-Xin,Xiao, Wei-Lie,Huang, Sheng-Xiong,Lou, Li-Guang,&Sun, Han-Dong.(2008).Kadcoccilactones K-R, triterpenoids from Kadsura coccinea.TETRAHEDRON,64(51),11673-11679. |
| MLA | Gao, Xue-Mei,et al."Kadcoccilactones K-R, triterpenoids from Kadsura coccinea".TETRAHEDRON 64.51(2008):11673-11679. |
入库方式： OAI收割
来源：上海药物研究所
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