Characterization and quantification of eight water-soluble constituents in tubers of Pinellia ternata and in tea granules from the Chinese multiherb remedy Xiaochaihu-tang
文献类型：期刊论文
| 作者 | Chen, Ping; Li, Chuan ; Liang, Shipiao; Song, Guoqiang; Sun, Yan; Shi, Yanhong; Xu, Songlin; Zhang, Jiwen; Sheng, Shuqun; Yang, Yiming
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| 刊名 | JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
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| 出版日期 | 2006-11-07 |
| 卷号 | 843期号:2页码:183-193 |
| 关键词 | LC-hyphenated techniques Xiaochaihu-tang Pinellia ternate |
| ISSN号 | 1570-0232 |
| DOI | 10.1016/j.jchromb.2006.05.028 |
| 文献子类 | Article |
| 英文摘要 | In traditional Chinese medicine, multiple herbs are usually used in combination to generate the joint actions of a multiherb remedy. The recent development of LC-hyphenated techniques enables efficient and rapid profiling of the chemical constituent in extracts from multiherb remedies. Xiaochaihu-tang is a seven-herb remedy that has attracted a great deal of attention for reported ability to treat liver dysfunction. Dried tubers of Pinellia ternata (banxia in Chinese) is one of the ingredients, but its chemical contribution to Xiaochaihu-tang remains poorly understood. In the study presented here, LC-UV-MS, LC-MS-MS, and LC-NMR were used in a complementary manner to determine the nature and content of eight water-soluble constituents of banxia and their presence in various tea granules from Xiaochaihu-tang. Among the eight chemicals identified in banxia, cytidine, adenosine, tryptophan, uridine, and adenine are reported for the first time, while tyrosine, guanosine, and phenylalanine were previously described. These chemicals are also present in all of the samples of Xiaochaihu-tang granules, and the amounts of the chemicals ingested due to a daily dose of the multiherb remedies range from 0.008 to 6.3 mg, (c) 2006 Elsevier B.V. All rights reserved. |
| WOS关键词 | MAGNETIC-RESONANCE-SPECTROSCOPY ; CHROMATOGRAPHY MASS-SPECTROMETRY ; LIQUID-CHROMATOGRAPHY ; SHOSAIKO-TO ; LIVER-DISEASE ; DAISAIKO-TO ; HUMAN URINE ; NUTRITIONAL THERAPY ; HERBAL MEDICINES ; IDENTIFICATION |
| WOS研究方向 | Biochemistry & Molecular Biology ; Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000242361400008 |
| 出版者 | ELSEVIER SCIENCE BV |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/273449]  |
| 专题 | 上海药物代谢研究中心 |
| 通讯作者 | Li, Chuan |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai Inst Biol Sci, Shanghai 201203, Peoples R China 2.Chengdu Univ Tradit Chinese Med, Chengdu 610075, Sichuan, Peoples R China 3.Chinese Acad Sci, Grad Sch, Shanghai, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chen, Ping,Li, Chuan,Liang, Shipiao,et al. Characterization and quantification of eight water-soluble constituents in tubers of Pinellia ternata and in tea granules from the Chinese multiherb remedy Xiaochaihu-tang[J]. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES,2006,843(2):183-193. |
| APA | Chen, Ping.,Li, Chuan.,Liang, Shipiao.,Song, Guoqiang.,Sun, Yan.,...&Li, Min.(2006).Characterization and quantification of eight water-soluble constituents in tubers of Pinellia ternata and in tea granules from the Chinese multiherb remedy Xiaochaihu-tang.JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES,843(2),183-193. |
| MLA | Chen, Ping,et al."Characterization and quantification of eight water-soluble constituents in tubers of Pinellia ternata and in tea granules from the Chinese multiherb remedy Xiaochaihu-tang".JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES 843.2(2006):183-193. |
入库方式： OAI收割
来源：上海药物研究所
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