Advances in research on nanotechnology for enhancing the absorption of poorly water-soluble drugs
文献类型：期刊论文
| 作者 | WANG Qin2; GU Wang-wen1
|
| 刊名 | Pharmaceutical Care and Research
 |
| 出版日期 | 2009 |
| 卷号 | 9期号:1页码:48-51 |
| 关键词 | nanotechnology poorly water-soluble drugs biological availability review |
| ISSN号 | 1671-2838 |
| 其他题名 | 应用纳米技术增加难溶性药物吸收的研究进展 |
| 文献子类 | Review |
| 英文摘要 | The development of some new technologies such as high-throughput screening has led to an increase in the number of poorly water-soluble drug candidates in the recent research and development of drugs. The nanotechnology provided an effective tool to improve aqueous solubility, dissolution rate and subsequent oral bioavailability and decreased food effect by decreasing the grain size of drugs. The methods of preparing nanoformulations, commercialized nanotechnologies and FDA ap-proved marketed products are reviewed in this article. The nanotechnology is a promising approach to enhance the oral absorption of drugs of biopharmaceutical classification system(BCS)Ⅱ. |
| WOS研究方向 | Pharmacology & Pharmacy (provided by Clarivate Analytics) |
| 语种 | 中文 |
| CSCD记录号 | CSCD:3571544 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/268026]  |
| 专题 | 药物制剂研究中心 |
| 通讯作者 | GU Wang-wen |
| 作者单位 | 1.Department of Pharmaceutical Preparation, Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 201203, China, Shanghai 201203, China. 2.Department of Pharmacy,Renji Hospital affiliated to College of Medicine,Shanghai Jiaotong University,Shanghai 200001, China, Shanghai 200001, China.; |
| 推荐引用方式 GB/T 7714 | WANG Qin,GU Wang-wen. Advances in research on nanotechnology for enhancing the absorption of poorly water-soluble drugs[J]. Pharmaceutical Care and Research,2009,9(1):48-51. |
| APA | WANG Qin,&GU Wang-wen.(2009).Advances in research on nanotechnology for enhancing the absorption of poorly water-soluble drugs.Pharmaceutical Care and Research,9(1),48-51. |
| MLA | WANG Qin,et al."Advances in research on nanotechnology for enhancing the absorption of poorly water-soluble drugs".Pharmaceutical Care and Research 9.1(2009):48-51. |
入库方式： OAI收割
来源：上海药物研究所
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