Ductile Biodegradable Mg-Based Metallic Glasses with Excellent Biocompatibility
文献类型：期刊论文
| 作者 | Yu, Hai-Jun1,4 ; Wang, Jun-Qiang1; Shi, Xue-Tao1; Louzguine-Luzgin, Dmitri V.1; Wu, Hong-Kai1,3; Perepezko, John H.1,2
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| 刊名 | ADVANCED FUNCTIONAL MATERIALS
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| 出版日期 | 2013-10-11 |
| 卷号 | 23期号:38页码:4793-4800 |
| ISSN号 | 1616-301X |
| 关键词 | metallic glasses biomedical x nanostructures |
| DOI | 10.1002/adfm.201203738 |
| 文献子类 | Article |
| 英文摘要 | Magnesium-based metallic glasses (MMGs) show intriguing potentials for application as implantable biomaterials owing to their disordered atomic structure, good biodegradability, low elastic modulus, high strength, and large elasticity. However, despite of all these advantages, their brittleness is their Achilles' heel, which severely limits their application as biomedical materials. In the current study, a significantly improved ductility of MMGs under bending and tensile loading through minor alloying with rare-earth element ytterbium (Yb) at an atomic concentration of 2 and 4% is reported. The enhanced ductility is attributed to the increased density of shear bands close to fracture end and larger plastic zones on the fracture surface. In comparison with that of Yb-free control, in vitro cell culture study confirms an improved biocompatibility of MMGs alloyed with Yb as determined by MTT, live-dead, and cytoskeleton staining assays, respectively. |
| WOS关键词 | IN-VITRO CORROSION ; MAGNESIUM ALLOY ; CA ALLOYS ; PART I ; DEFORMATION ; TEMPERATURE ; IMPLANTS ; BEHAVIOR ; CALCIUM ; BONE |
| 资助项目 | Fusion Research Fund[00000000] ; World Premier International Research Center Initiative-Advanced Institute of Materials Research (WPI-AIMR), MEXT, Japan[00000000] |
| WOS研究方向 | Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics |
| 语种 | 英语 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| WOS记录号 | WOS:000327479200004 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/277422]  |
| 专题 | 药物制剂研究中心 |
| 通讯作者 | Wang, Jun-Qiang |
| 作者单位 | 1.Tohoku Univ, WPI Adv Inst Mat Res, Sendai, Miyagi 9808577, Japan; 2.Univ Wisconsin, Dept Mat Sci & Engn, Madison, WI 53706 USA 3.Hong Kong Univ Sci & Technol, Dept Chem, Hong Kong, Hong Kong, Peoples R China; 4.Chinese Acad Sci, Shanghai Inst Mat Med, Ctr Pharmaceut, Shanghai 201203, Peoples R China; |
| 推荐引用方式 GB/T 7714 | Yu, Hai-Jun,Wang, Jun-Qiang,Shi, Xue-Tao,et al. Ductile Biodegradable Mg-Based Metallic Glasses with Excellent Biocompatibility[J]. ADVANCED FUNCTIONAL MATERIALS,2013,23(38):4793-4800. |
| APA | Yu, Hai-Jun,Wang, Jun-Qiang,Shi, Xue-Tao,Louzguine-Luzgin, Dmitri V.,Wu, Hong-Kai,&Perepezko, John H..(2013).Ductile Biodegradable Mg-Based Metallic Glasses with Excellent Biocompatibility.ADVANCED FUNCTIONAL MATERIALS,23(38),4793-4800. |
| MLA | Yu, Hai-Jun,et al."Ductile Biodegradable Mg-Based Metallic Glasses with Excellent Biocompatibility".ADVANCED FUNCTIONAL MATERIALS 23.38(2013):4793-4800. |
入库方式： OAI收割
来源：上海药物研究所
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