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Intracellular pH-activated PEG-b-PDPA wormlike micelles for hydrophobic drug delivery

文献类型：期刊论文

作者Yu, Haijun1; Xu, Zhiai2; Wang, Dangge1; Chen, Xianzhi1; Zhang, Zhiwen1; Yin, Qi1; Li, Yaping1
刊名POLYMER CHEMISTRY
出版日期2013-10-07
卷号4期号:19页码:5052-5055
ISSN号1759-9954
DOI10.1039/c3py00849e
文献子类Article
英文摘要Wormlike micelles with intracellular pH-activating properties were developed. The micelles remained in a "silent" state at physiological pH conditions (i.e. pH 7.4), but were activated in the acidic microenvironment of endocytic vesicles. The wormlike micelles could be employed as nanovectors for the intracellular delivery of hydrophobic drugs for cancer therapy.
WOS关键词NILE-RED ; NANOPARTICLES ; CANCER ; COPOLYMERS ; SYSTEMS ; SIRNA
资助项目National Basic Research Program of China[2013CB932704] ; National Basic Research Program of China[2010CB934000] ; National Basic Research Program of China[2012CB932502] ; National Natural Science Foundation of China[81102388] ; National Natural Science Foundation of China[81270047]
WOS研究方向Polymer Science
语种英语
WOS记录号WOS:000324849900005
出版者ROYAL SOC CHEMISTRY
源URL[http://119.78.100.183/handle/2S10ELR8/277424]  
专题药物制剂研究中心
通讯作者Li, Yaping
作者单位1.Chinese Acad Sci, Shanghai Inst Mat Med, Ctr Pharmaceut, Shanghai 201203, Peoples R China;
2.E China Normal Univ, Dept Chem, Shanghai 200241, Peoples R China
推荐引用方式
GB/T 7714		 Yu, Haijun,Xu, Zhiai,Wang, Dangge,et al. Intracellular pH-activated PEG-b-PDPA wormlike micelles for hydrophobic drug delivery[J]. POLYMER CHEMISTRY,2013,4(19):5052-5055.
APA Yu, Haijun.,Xu, Zhiai.,Wang, Dangge.,Chen, Xianzhi.,Zhang, Zhiwen.,...&Li, Yaping.(2013).Intracellular pH-activated PEG-b-PDPA wormlike micelles for hydrophobic drug delivery.POLYMER CHEMISTRY,4(19),5052-5055.
MLA Yu, Haijun,et al."Intracellular pH-activated PEG-b-PDPA wormlike micelles for hydrophobic drug delivery".POLYMER CHEMISTRY 4.19(2013):5052-5055.

入库方式： OAI收割

来源：上海药物研究所

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