Recent advances in topical ophthalmic drug delivery with lipid-based nanocarriers
文献类型：期刊论文
| 作者 | Gan, Li3; Wang, Jing2,3; Jiang, Min2,3; Bartlett, Hanah1; Ouyang, Defang1; Eperjesi, Frank1; Liu, Jianping2; Gan, Yong3
|
| 刊名 | DRUG DISCOVERY TODAY
 |
| 出版日期 | 2013-03 |
| 卷号 | 18期号:5-6页码:290-297 |
| ISSN号 | 1359-6446 |
| DOI | 10.1016/j.drudis.2012.10.005 |
| 文献子类 | Review |
| 英文摘要 | Ocular barriers and the poor water solubility of drug candidates present a number of problems for the development of ocular drug delivery systems. Recently, the emergence of lipid-based nanocarriers has provided a viable means of enhancing the bioavailability of ophthalmic formulations. A number of these formulations have been found to be clinically active and several others are currently undergoing clinical trials. In this review, the advantages of lipid-based nanocarriers as non-invasive topical ocular drug delivery systems are presented. Many systems, including emulsions, liposomes, cubosomes, niosomes and other lipid-based nanocarriers, are reviewed. |
| WOS关键词 | OCULAR DELIVERY ; IN-VIVO ; DRY EYE ; CYCLOSPORINE-A ; CONJUNCTIVAL EPITHELIA ; PRECORNEAL RETENTION ; OPTOMETRIC PRACTICES ; POTENTIAL CARRIERS ; SYSTEM ; LIPOSOMES |
| 资助项目 | National Natural Sciences Foundation of China[81102387] ; Natural Sciences Foundation of Shanghai China[11ZR1444700] ; National Science and Technology Major Project Key New Drug Creation and Manufacturing Program[2009ZX09301-001] ; National Basic Research Program of China[2009CB930300] |
| WOS研究方向 | Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000316427000010 |
| 出版者 | ELSEVIER SCI LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/277713]  |
| 专题 | 药物制剂研究中心 |
| 通讯作者 | Gan, Yong |
| 作者单位 | 1.Aston Univ, Sch Life & Hlth Sci, Ophthalm Res Grp, Birmingham B4 7ET, W Midlands, England 2.China Pharmaceut Univ, Sch Pharm, Nanjing 210009, Jiangsu, Peoples R China; 3.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China; |
| 推荐引用方式 GB/T 7714 | Gan, Li,Wang, Jing,Jiang, Min,et al. Recent advances in topical ophthalmic drug delivery with lipid-based nanocarriers[J]. DRUG DISCOVERY TODAY,2013,18(5-6):290-297. |
| APA | Gan, Li.,Wang, Jing.,Jiang, Min.,Bartlett, Hanah.,Ouyang, Defang.,...&Gan, Yong.(2013).Recent advances in topical ophthalmic drug delivery with lipid-based nanocarriers.DRUG DISCOVERY TODAY,18(5-6),290-297. |
| MLA | Gan, Li,et al."Recent advances in topical ophthalmic drug delivery with lipid-based nanocarriers".DRUG DISCOVERY TODAY 18.5-6(2013):290-297. |
入库方式： OAI收割
来源：上海药物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。