Overcoming multidrug resistance (MDR) in cancer by nanotechnology
文献类型：期刊论文
| 作者 | Bu HuiHui; Gao Yu; Li YaPing
|
| 刊名 | SCIENCE CHINA-CHEMISTRY
 |
| 出版日期 | 2010-11 |
| 卷号 | 53期号:11页码:2226-2232 |
| 关键词 | nanotechnology nanoparticles multidrug resistance chemotherapeutic drugs cancer drug delivery system |
| ISSN号 | 1674-7291 |
| DOI | 10.1007/s11426-010-4142-5 |
| 文献子类 | Review |
| 英文摘要 | The emerging nanotechnology-based drug delivery holds tremendous potential to deliver chemotherapeutic drugs for treatment of multidrug resistance (MDR) cancer. This drug delivery system could improve the pharmacokinetic behavior of antitumor drugs, deliver chemotherapeutic drugs to target sites, control release of drugs, and reduce the systemic toxicity of drugs in MDR cancer. This review addresses the use of nanotechnology to overcome MDR classified on the bases of the fundamental mechanisms of MDR and various approaches to deliver drugs for treatment of MDR cancer. |
| WOS关键词 | SENSITIVE POLYMERIC MICELLES ; DOUBLE-STRAND BREAKS ; DRUG-RESISTANCE ; P-GLYCOPROTEIN ; DNA-DAMAGE ; IN-VIVO ; MAGNETIC NANOPARTICLES ; PACLITAXEL DELIVERY ; TARGETED DELIVERY ; ANTICANCER DRUG |
| 资助项目 | National Basic Research Program of China[2010CB934000] ; National Natural Science Foundation of China[30925041] ; Shanghai Nanomedicine Program[0852nm05700] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000284078200003 |
| 出版者 | SCIENCE PRESS |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/278725]  |
| 专题 | 药物制剂研究中心 |
| 通讯作者 | Li YaPing |
| 作者单位 | Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Bu HuiHui,Gao Yu,Li YaPing. Overcoming multidrug resistance (MDR) in cancer by nanotechnology[J]. SCIENCE CHINA-CHEMISTRY,2010,53(11):2226-2232. |
| APA | Bu HuiHui,Gao Yu,&Li YaPing.(2010).Overcoming multidrug resistance (MDR) in cancer by nanotechnology.SCIENCE CHINA-CHEMISTRY,53(11),2226-2232. |
| MLA | Bu HuiHui,et al."Overcoming multidrug resistance (MDR) in cancer by nanotechnology".SCIENCE CHINA-CHEMISTRY 53.11(2010):2226-2232. |
入库方式： OAI收割
来源：上海药物研究所
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