中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Recent Advances on the Solubility - Enhancing Fusion Tags for Recombinant Protein Expression

文献类型:期刊论文

作者Li Xiangkui2; Fan Cuiying1; Cui Yajun2; Liu Xuan1
刊名Biotechnology
出版日期2013
卷号23期号:2页码:93-97
关键词fusion expression solubility - enhancing tag recombinant protein application
ISSN号1004-311X
其他题名重组蛋白可溶性表达促进标签的研究进展
文献子类Review
英文摘要The expression of recombinant proteins plays an important role in promoting the development of modern biological technology. A powerful tool for structural and functional studies of important proteins,especially proteins of human beings,could be provided by producing heterologous proteins in the hosts. The application of solubility - enhancing tags could overcome the soluble problem in expressing recombinant proteins. And,the yield,structure modification and purification of recombinant proteins could be influenced by the fusion partners. In the present review,the characteristics of several common solubility enhancers were introduced. The recent advances on the solubility - enhancing fusion tags were showed and the potential problems in their application were discussed. At last,the future was prospected. This review might be helpful for researchers in choosing suitable tags in their experiments.
WOS研究方向Genetics & Heredity (provided by Clarivate Analytics)
语种中文
CSCD记录号CSCD:4839548
源URL[http://119.78.100.183/handle/2S10ELR8/267779]  
专题上海中药现代化研究中心
作者单位1.Shanghai Institute of Materia Medica,Chinese Academy of Sciences, Shanghai 201203, China.
2.Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.;
推荐引用方式
GB/T 7714
Li Xiangkui,Fan Cuiying,Cui Yajun,et al. Recent Advances on the Solubility - Enhancing Fusion Tags for Recombinant Protein Expression[J]. Biotechnology,2013,23(2):93-97.
APA Li Xiangkui,Fan Cuiying,Cui Yajun,&Liu Xuan.(2013).Recent Advances on the Solubility - Enhancing Fusion Tags for Recombinant Protein Expression.Biotechnology,23(2),93-97.
MLA Li Xiangkui,et al."Recent Advances on the Solubility - Enhancing Fusion Tags for Recombinant Protein Expression".Biotechnology 23.2(2013):93-97.

入库方式: OAI收割

来源:上海药物研究所

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