Recent Advances on the Solubility - Enhancing Fusion Tags for Recombinant Protein Expression
文献类型:期刊论文
作者 | Li Xiangkui2; Fan Cuiying1; Cui Yajun2; Liu Xuan1 |
刊名 | Biotechnology
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出版日期 | 2013 |
卷号 | 23期号:2页码:93-97 |
关键词 | fusion expression solubility - enhancing tag recombinant protein application |
ISSN号 | 1004-311X |
其他题名 | 重组蛋白可溶性表达促进标签的研究进展 |
文献子类 | Review |
英文摘要 | The expression of recombinant proteins plays an important role in promoting the development of modern biological technology. A powerful tool for structural and functional studies of important proteins,especially proteins of human beings,could be provided by producing heterologous proteins in the hosts. The application of solubility - enhancing tags could overcome the soluble problem in expressing recombinant proteins. And,the yield,structure modification and purification of recombinant proteins could be influenced by the fusion partners. In the present review,the characteristics of several common solubility enhancers were introduced. The recent advances on the solubility - enhancing fusion tags were showed and the potential problems in their application were discussed. At last,the future was prospected. This review might be helpful for researchers in choosing suitable tags in their experiments. |
WOS研究方向 | Genetics & Heredity (provided by Clarivate Analytics) |
语种 | 中文 |
CSCD记录号 | CSCD:4839548 |
源URL | [http://119.78.100.183/handle/2S10ELR8/267779] ![]() |
专题 | 上海中药现代化研究中心 |
作者单位 | 1.Shanghai Institute of Materia Medica,Chinese Academy of Sciences, Shanghai 201203, China. 2.Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.; |
推荐引用方式 GB/T 7714 | Li Xiangkui,Fan Cuiying,Cui Yajun,et al. Recent Advances on the Solubility - Enhancing Fusion Tags for Recombinant Protein Expression[J]. Biotechnology,2013,23(2):93-97. |
APA | Li Xiangkui,Fan Cuiying,Cui Yajun,&Liu Xuan.(2013).Recent Advances on the Solubility - Enhancing Fusion Tags for Recombinant Protein Expression.Biotechnology,23(2),93-97. |
MLA | Li Xiangkui,et al."Recent Advances on the Solubility - Enhancing Fusion Tags for Recombinant Protein Expression".Biotechnology 23.2(2013):93-97. |
入库方式: OAI收割
来源:上海药物研究所
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