The Basement Membrane and Metastasis
文献类型：期刊论文
| 作者 | ZHOU Jin; CHEN Yi ; DING Jian
|
| 刊名 | Progress in Physiological Sciences
 |
| 出版日期 | 2006 |
| 卷号 | 37期号:4页码:307-312 |
| 关键词 | metastasis basement membrane matrix metalloproteinase heparanase |
| ISSN号 | 0559-7765 |
| 其他题名 | 基底膜和肿瘤转移 |
| 文献子类 | Review |
| 英文摘要 | The basement membrane (BM) is a specialised form of extracellular matrix (ECM), which is a major barrier to tumor cells during metastasis. The component of basement membrane plays important role in regulating tumor metastasis by interacting with cell surface receptor integrins. On the other hand, tumor cells secrete Matrix metalloproteinase and Heparanase to degrade the extracellular matrix components, as well as adjust the expression of surface receptor-integrins to facilitate migration in basement membrane and adhesion to target organs. Understanding of the cell-ECM interaction may offer us new strategy for drug discovery. |
| 资助项目 | 国家自然科学基金资助课题[00000000] |
| WOS研究方向 | Oncology (provided by Clarivate Analytics) |
| 语种 | 中文 |
| CSCD记录号 | CSCD:2539098 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/268261]  |
| 专题 | 上海中药现代化研究中心 |
| 作者单位 | Division of Anti-Tumor Pharmacology, Shanghai Institute of Materia Medica, Shanghai 201203, China. |
| 推荐引用方式 GB/T 7714 | ZHOU Jin,CHEN Yi,DING Jian. The Basement Membrane and Metastasis[J]. Progress in Physiological Sciences,2006,37(4):307-312. |
| APA | ZHOU Jin,CHEN Yi,&DING Jian.(2006).The Basement Membrane and Metastasis.Progress in Physiological Sciences,37(4),307-312. |
| MLA | ZHOU Jin,et al."The Basement Membrane and Metastasis".Progress in Physiological Sciences 37.4(2006):307-312. |
入库方式： OAI收割
来源：上海药物研究所
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