Studies on chemical constituents possessing DNA cleavage activity
文献类型：期刊论文
| 作者 | Xiao Kai; Xuan Lijiang ; Xu Yaming; Bai Donglu
|
| 刊名 | Chinese Traditional and Herbal Drugs
 |
| 出版日期 | 2003 |
| 卷号 | 34期号:3页码:203-206 |
| 关键词 | Polygonum bistorta L. water-soluble constituents DNA cleavage activity |
| ISSN号 | 0253-2670 |
| 其他题名 | 拳参的DNA裂解活性成分研究 |
| 文献子类 | Article |
| 英文摘要 | Object To study the chemical structures and DNA cleavage activity of the water-soluble constituents from Polygonum bistorta L. Methods To isolate the constituents by reverse phase chro-matography, and characterize their structures by the analysis of chemical property and spectral data. Results Ten compounds were isolated from the 60% acetone extract of the rhizoma from P. bistorta. Their structures were elucidated as gallic acid ( I ), tryptophan (Ⅱ), 2, 6-dihydroy-bezoic acid (Ⅲ), ( + )-cat-echin (Ⅳ), chlorogenic acid (V), ( - )-epicatechin-5-O-beta-D-glucopyranoside (Ⅵ), ( + )-catechin-7-O-beta-D-glucopyranoside (Vff ) , l-beta-O-beta-D-glucopyranosyl-4, 5-dihydroxy-phenyl)-ethanone (Ⅶ), ( + )-cate-chin-5-O-p-D-glucopyranoside ( K ) and ( - )-epicatechin (X), respectively. Conclusion Compounds I ,-I , V - X were isolated from the plant for the first time. Compounds I , Ⅳ , Ⅵ , Ⅶ, Ⅸ , X showed significant DNA cleavage activity. |
| WOS研究方向 | General & Internal Medicine (provided by Clarivate Analytics) |
| 语种 | 中文 |
| CSCD记录号 | CSCD:1334218 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/268446]  |
| 专题 | 上海中药现代化研究中心 院士及顾问专家 |
| 作者单位 | Shanghai Institute of Materia Medica, Shanghai Institute for Life Sciences, CAS, Shanghai 200433, China. |
| 推荐引用方式 GB/T 7714 | Xiao Kai,Xuan Lijiang,Xu Yaming,et al. Studies on chemical constituents possessing DNA cleavage activity[J]. Chinese Traditional and Herbal Drugs,2003,34(3):203-206. |
| APA | Xiao Kai,Xuan Lijiang,Xu Yaming,&Bai Donglu.(2003).Studies on chemical constituents possessing DNA cleavage activity.Chinese Traditional and Herbal Drugs,34(3),203-206. |
| MLA | Xiao Kai,et al."Studies on chemical constituents possessing DNA cleavage activity".Chinese Traditional and Herbal Drugs 34.3(2003):203-206. |
入库方式： OAI收割
来源：上海药物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。