Studies on water-soluble constituents in rhizome of Polygonum cuspidatum
文献类型：期刊论文
| 作者 | Xiao Kai; Xuan Lijiang ; Xu Yaming; Bai Donglu
|
| 刊名 | Chinese Traditional and Herbal Drugs
 |
| 出版日期 | 2003 |
| 卷号 | 34期号:6页码:496-498 |
| 关键词 | polygonum cuspidatum Sieb. et Zucc. water-soluble constituents bioactivity |
| ISSN号 | 0253-2670 |
| 其他题名 | 虎杖的水溶性成分研究 |
| 文献子类 | Article |
| 英文摘要 | Object To study the chemical structures and bioactivity of the water-soluble constituents from Polygonum cuspidatum Sieb. et Zucc Methods To isolate the constituents by reverse phase meth-ods , and characterize their structures by the analysis of chemical property and spectral data. Results Six compounds were isolated from the 60% aqueous acetone extract from the rhizome of P. cuspidatum. Their structures were elucidated as reveratrol ( I ); piceid ( I ); 2, 3-dihydro-2-(4'-O-beta-D-glucopyranosyl-3'-methoxy-phenyl)-3-hydroxymethyl-5-(3-hydroxypropyl)-7-methoxybenzofuran ( I ) ; 2, 6-dimethoxy-^-hydroquinOne-l-0-beta-D-glucopyranoside (W)j 5, 7-dihydroxy-isobenzofuran (V) and 5, 7-dihydroxy-isobenzofuran-7-0-beta-D-glucopyranoside ( VI ) , respectively. Conclusion Compounds I - VI are isolated from the plant for the first time. Compounds I-VI show no DNA cleavage activity. Compound II exhibits weak cytotoxicity against two human cancer cell lines (KB and MCF-7) in vitro. |
| WOS研究方向 | Pharmacology & Pharmacy (provided by Clarivate Analytics) |
| 语种 | 中文 |
| CSCD记录号 | CSCD:1248958 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/268448]  |
| 专题 | 上海中药现代化研究中心 院士及顾问专家 |
| 作者单位 | Shanghai Institute of Materia Medica, Shanghai Institute for Biological Sciences, CAS, Shanghai 200031, China. |
| 推荐引用方式 GB/T 7714 | Xiao Kai,Xuan Lijiang,Xu Yaming,et al. Studies on water-soluble constituents in rhizome of Polygonum cuspidatum[J]. Chinese Traditional and Herbal Drugs,2003,34(6):496-498. |
| APA | Xiao Kai,Xuan Lijiang,Xu Yaming,&Bai Donglu.(2003).Studies on water-soluble constituents in rhizome of Polygonum cuspidatum.Chinese Traditional and Herbal Drugs,34(6),496-498. |
| MLA | Xiao Kai,et al."Studies on water-soluble constituents in rhizome of Polygonum cuspidatum".Chinese Traditional and Herbal Drugs 34.6(2003):496-498. |
入库方式： OAI收割
来源：上海药物研究所
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