中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Comparative analysis of seven marine biological source of mineral drugs

文献类型:期刊论文

作者Si Wei1; A Runa1; Li Shangrong2; Zhang Jingxian2; Wu Wanying2; Cui Yajun1
刊名China Journal of Chinese Materia Medica
出版日期2014
卷号39期号:17页码:3321-3325
关键词marine biological source of mineral drugs X-ray powder diffraction calcium carbonate total amino acids EDTA titration method ultraviolot spectrophotometry method
ISSN号1001-5302
其他题名7种海洋矿物药的比较分析研究
文献子类Article
英文摘要The marine biological source of mineral drugs recorded in Chinese Pharmacopoeia (2010 version) mainly including pearl,nacre,clam shell,common oyster shell,ark shell,cuttle bone,and sea-ear shell are widely used in clinical. Calcium carbonate and a small amount of protein are the main components in this type of drugs. In this paper,a systematical and comparable study were carried out by determination of calcium carbonate by EDTA titration method,the crystal of calcium carbonate by X-Ray powder diffraction and the total amino acids (TAAs) of the hydrolyzed samples by ultraviolet spectrophotometry method. As a result,the crystal structure is calcite for common oyster shell,mixture of calcite and aragonite for nacre and sea-ear shell,aragonite for the other drugs. The content of calcium carbonate ranged from 86% to 96%. Cuttle bone has the highest amount of TAAs among the seven drugs which reached 1.7% while clam shell has the lowest content of 0. 16% on average. In conclusion, an effective method was developed for the quality control of marine mineral drugs by comprehensive analysis of calcium carbonate and TAAs in the seven marine mineral drugs.
资助项目国家高技术研究发展计划(863)项目[00000000] ; 2015年版药典标准提高项目[00000000]
WOS研究方向General & Internal Medicine (provided by Clarivate Analytics)
语种中文
CSCD记录号CSCD:5352432
源URL[http://119.78.100.183/handle/2S10ELR8/269301]  
专题上海中药现代化研究中心
作者单位1.Shanghai University of Traditional Chinese Medicine College of Traditional Chinese medicine, Shanghai 201203, China.;
2.National Engineering Laboratory for TCM Standardization Technology, Shanghai Research Center for Modernization of Traditional Chinese Medicine, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
推荐引用方式
GB/T 7714
Si Wei,A Runa,Li Shangrong,et al. Comparative analysis of seven marine biological source of mineral drugs[J]. China Journal of Chinese Materia Medica,2014,39(17):3321-3325.
APA Si Wei,A Runa,Li Shangrong,Zhang Jingxian,Wu Wanying,&Cui Yajun.(2014).Comparative analysis of seven marine biological source of mineral drugs.China Journal of Chinese Materia Medica,39(17),3321-3325.
MLA Si Wei,et al."Comparative analysis of seven marine biological source of mineral drugs".China Journal of Chinese Materia Medica 39.17(2014):3321-3325.

入库方式: OAI收割

来源:上海药物研究所

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