Withaphysanolide A, a novel C-27 norwithanolide skeleton, and other cytotoxic compounds from Physalis divericata
文献类型：期刊论文
| 作者 | Ma, Lei; Ali, Mumtaz; Arfan, Mohammad; Lou, Li-Guang ; Hu, Li-Hong
|
| 刊名 | TETRAHEDRON LETTERS
 |
| 出版日期 | 2007-01-15 |
| 卷号 | 48期号:3页码:449-452 |
| 关键词 | norwithanolides Physalis divericata withaphysanolide A cytotoxicity |
| ISSN号 | 0040-4039 |
| DOI | 10.1016/j.tetlet.2006.11.081 |
| 文献子类 | Article |
| 英文摘要 | A novel C-27 norwithasteroid, withaphysanolide A (1) containing a pyran ring was isolated from the aerial parts of Physalis divericata. Four known withaphysalins (2-5) and five physalins (6-10) were also isolated. The structural assignment for I was done based on spectroscopic and single-crystal X-ray diffraction data. Logical biosynthetic pathways were postulated. Compounds 6, 7, and 10 displayed potent cytotoxic activity against HCT-116 and H460 human cancer cell lines, with IC50 values less than 2.0 mu M. (c) 2006 Elsevier Ltd. All rights reserved. |
| WOS关键词 | VAR INDICA ; ANGULATA ; WITHANOLIDES ; LANCIFOLIA |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000243819100026 |
| 出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/273356]  |
| 专题 | 上海中药现代化研究中心 |
| 通讯作者 | Lou, Li-Guang |
| 作者单位 | 1.Univ Peshawar, Inst Chem Sci, Peshawar, Pakistan 2.Shanghai Inst Mat Med, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Ma, Lei,Ali, Mumtaz,Arfan, Mohammad,et al. Withaphysanolide A, a novel C-27 norwithanolide skeleton, and other cytotoxic compounds from Physalis divericata[J]. TETRAHEDRON LETTERS,2007,48(3):449-452. |
| APA | Ma, Lei,Ali, Mumtaz,Arfan, Mohammad,Lou, Li-Guang,&Hu, Li-Hong.(2007).Withaphysanolide A, a novel C-27 norwithanolide skeleton, and other cytotoxic compounds from Physalis divericata.TETRAHEDRON LETTERS,48(3),449-452. |
| MLA | Ma, Lei,et al."Withaphysanolide A, a novel C-27 norwithanolide skeleton, and other cytotoxic compounds from Physalis divericata".TETRAHEDRON LETTERS 48.3(2007):449-452. |
入库方式： OAI收割
来源：上海药物研究所
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