中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Characterization of phenolic compounds in the crude extract of Hedysarum multilugum by high-performance liquid chromatography with electrospray ionization tandem mass spectrometry

文献类型:期刊论文

作者Yang, Min; Wang, Wei; Sun, Jianghao; Zhao, Yuying; Liu, Yi; Liang, Hong; Guo, De-an
刊名RAPID COMMUNICATIONS IN MASS SPECTROMETRY
出版日期2007
卷号21期号:23页码:3833-3841
ISSN号0951-4198
DOI10.1002/rcm.3277
文献子类Article
英文摘要The fragmentation behavior of four types of phenolic compounds: coumestans, pterocarpenes, benzofurans and isoflavones, were studied using electrospray ionization multistage mass spectrometry (ESI-MSn) (n = 2-5) in negative ion mode. Losses of methyl (15 Da), CO (28 Da), CO2 (44 Da), isopropyl (43 Da) and isobutenyl (55 Da) were dominating fragmentation patterns. Different positions and numbers of the substituents also led to the different fragmentation behavior. These fragmentation rules were applied for the identification of constituents in methanolic extracts of Hedysarum multijugum, in which 29 compounds were characterized, including nine new compounds. The method established in this study could be applied to the comprehensive quality control of the herb and its formulations. It could also be applied to the biological and pharmacological research of traditional Chinese medicines. Copyright (c) 2007 John Wiley & Sons, Ltd.
WOS关键词MULTIJUGUM ; FLAVONOIDS ; ROOTS
WOS研究方向Biochemistry & Molecular Biology ; Chemistry ; Spectroscopy
语种英语
WOS记录号WOS:000251287200009
出版者JOHN WILEY & SONS LTD
源URL[http://119.78.100.183/handle/2S10ELR8/273419]  
专题上海中药现代化研究中心
通讯作者Liang, Hong
作者单位1.Chinese Acad Sci, Shanghai Inst Biol Sci, Shanghai Inst Mat Med, Shanghai Res Ctr TCM Modernizat, Shanghai 201203, Peoples R China
2.Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100083, Peoples R China
推荐引用方式
GB/T 7714
Yang, Min,Wang, Wei,Sun, Jianghao,et al. Characterization of phenolic compounds in the crude extract of Hedysarum multilugum by high-performance liquid chromatography with electrospray ionization tandem mass spectrometry[J]. RAPID COMMUNICATIONS IN MASS SPECTROMETRY,2007,21(23):3833-3841.
APA Yang, Min.,Wang, Wei.,Sun, Jianghao.,Zhao, Yuying.,Liu, Yi.,...&Guo, De-an.(2007).Characterization of phenolic compounds in the crude extract of Hedysarum multilugum by high-performance liquid chromatography with electrospray ionization tandem mass spectrometry.RAPID COMMUNICATIONS IN MASS SPECTROMETRY,21(23),3833-3841.
MLA Yang, Min,et al."Characterization of phenolic compounds in the crude extract of Hedysarum multilugum by high-performance liquid chromatography with electrospray ionization tandem mass spectrometry".RAPID COMMUNICATIONS IN MASS SPECTROMETRY 21.23(2007):3833-3841.

入库方式: OAI收割

来源:上海药物研究所

浏览0
下载0
收藏0
其他版本

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。