Characterization of phenolic compounds in the crude extract of Hedysarum multilugum by high-performance liquid chromatography with electrospray ionization tandem mass spectrometry
文献类型：期刊论文
| 作者 | Yang, Min; Wang, Wei; Sun, Jianghao; Zhao, Yuying; Liu, Yi; Liang, Hong; Guo, De-an
|
| 刊名 | RAPID COMMUNICATIONS IN MASS SPECTROMETRY
 |
| 出版日期 | 2007 |
| 卷号 | 21期号:23页码:3833-3841 |
| ISSN号 | 0951-4198 |
| DOI | 10.1002/rcm.3277 |
| 文献子类 | Article |
| 英文摘要 | The fragmentation behavior of four types of phenolic compounds: coumestans, pterocarpenes, benzofurans and isoflavones, were studied using electrospray ionization multistage mass spectrometry (ESI-MSn) (n = 2-5) in negative ion mode. Losses of methyl (15 Da), CO (28 Da), CO2 (44 Da), isopropyl (43 Da) and isobutenyl (55 Da) were dominating fragmentation patterns. Different positions and numbers of the substituents also led to the different fragmentation behavior. These fragmentation rules were applied for the identification of constituents in methanolic extracts of Hedysarum multijugum, in which 29 compounds were characterized, including nine new compounds. The method established in this study could be applied to the comprehensive quality control of the herb and its formulations. It could also be applied to the biological and pharmacological research of traditional Chinese medicines. Copyright (c) 2007 John Wiley & Sons, Ltd. |
| WOS关键词 | MULTIJUGUM ; FLAVONOIDS ; ROOTS |
| WOS研究方向 | Biochemistry & Molecular Biology ; Chemistry ; Spectroscopy |
| 语种 | 英语 |
| WOS记录号 | WOS:000251287200009 |
| 出版者 | JOHN WILEY & SONS LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/273419]  |
| 专题 | 上海中药现代化研究中心 |
| 通讯作者 | Liang, Hong |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Biol Sci, Shanghai Inst Mat Med, Shanghai Res Ctr TCM Modernizat, Shanghai 201203, Peoples R China 2.Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100083, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yang, Min,Wang, Wei,Sun, Jianghao,et al. Characterization of phenolic compounds in the crude extract of Hedysarum multilugum by high-performance liquid chromatography with electrospray ionization tandem mass spectrometry[J]. RAPID COMMUNICATIONS IN MASS SPECTROMETRY,2007,21(23):3833-3841. |
| APA | Yang, Min.,Wang, Wei.,Sun, Jianghao.,Zhao, Yuying.,Liu, Yi.,...&Guo, De-an.(2007).Characterization of phenolic compounds in the crude extract of Hedysarum multilugum by high-performance liquid chromatography with electrospray ionization tandem mass spectrometry.RAPID COMMUNICATIONS IN MASS SPECTROMETRY,21(23),3833-3841. |
| MLA | Yang, Min,et al."Characterization of phenolic compounds in the crude extract of Hedysarum multilugum by high-performance liquid chromatography with electrospray ionization tandem mass spectrometry".RAPID COMMUNICATIONS IN MASS SPECTROMETRY 21.23(2007):3833-3841. |
入库方式： OAI收割
来源：上海药物研究所
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