Simultaneous determination, of six major constituents in the stems of Kadsura heteroclita by LC-DAD
文献类型：期刊论文
| 作者 | Wang, Wei; Liu, Jinzhi; Yang, Min; Sun, Jianghao; Wang, Xiaoming; Liu, Rongxia; Guo, Dean
|
| 刊名 | CHROMATOGRAPHIA
 |
| 出版日期 | 2006-09 |
| 卷号 | 64期号:5-6页码:297-302 |
| 关键词 | column liquid chromatography quality control triterpenoid compounds Kadsura heteroclita |
| ISSN号 | 0009-5893 |
| DOI | 10.1365/s10337-006-0031-7 |
| 文献子类 | Article |
| 英文摘要 | The stem of Kadsura heteroclita is a traditional Chinese medicine with a variety of biological activities. For efficient monitoring of the quality of the herb, a simple, rapid, and accurate HPLC method has been developed for simultaneous determination of five cyclolanostane triterpenoid compounds (schisanlactone E, nigranoic acid, schisandronic acid, and heteroclitalactones A and D) and one tetrahydrofuran lignan (d-epigalbacin) in the stems of K. heteroclita. These six compounds were separated on a C-18 column by elution with a mobile-phase gradient prepared from acetonitrile and 0.05% (v/v) aqueous phosphoric acid. The flow rate was 1.0 mL min(-1) and the detection wavelength was 210 nm. The recovery of the method was in the range 95.03-102.19% and a good linear relationship (r(2) > 0.9999) was obtained between response and compound concentration over a relatively wide range. The method was successfully applied to analysis of the herb collected at different stages of growth. |
| WOS关键词 | LIQUID-CHROMATOGRAPHY ; SCHISANDRA-CHINENSIS ; LIGNAN CONSTITUENTS ; ACID |
| WOS研究方向 | Biochemistry & Molecular Biology ; Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000241222200011 |
| 出版者 | SPRINGER HEIDELBERG |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/273505]  |
| 专题 | 上海中药现代化研究中心 |
| 通讯作者 | Guo, Dean |
| 作者单位 | 1.Peking Univ, Shenzhen Hosp, Shenzhen 518000, Guangdong, Peoples R China 2.Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100083, Peoples R China 3.Chinese Acad Sci, Shanghai Inst Biol Sci, Shanghai Inst Mat Med, Shanghai Res Ctr Modernizat Tradit Chinese Med, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Wei,Liu, Jinzhi,Yang, Min,et al. Simultaneous determination, of six major constituents in the stems of Kadsura heteroclita by LC-DAD[J]. CHROMATOGRAPHIA,2006,64(5-6):297-302. |
| APA | Wang, Wei.,Liu, Jinzhi.,Yang, Min.,Sun, Jianghao.,Wang, Xiaoming.,...&Guo, Dean.(2006).Simultaneous determination, of six major constituents in the stems of Kadsura heteroclita by LC-DAD.CHROMATOGRAPHIA,64(5-6),297-302. |
| MLA | Wang, Wei,et al."Simultaneous determination, of six major constituents in the stems of Kadsura heteroclita by LC-DAD".CHROMATOGRAPHIA 64.5-6(2006):297-302. |
入库方式： OAI收割
来源：上海药物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。