Simultaneous quantification of six major phenolic acids in the roots of Salvia miltiorrhiza and four related traditional Chinese medicinal preparations by HPLC-DAD method
文献类型:期刊论文
作者 | Liu, AH; Li, L![]() ![]() |
刊名 | JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
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出版日期 | 2006-04-11 |
卷号 | 41期号:1页码:48-56 |
关键词 | RP-HPLC Salvia miltiorrhiza phenolic acid traditional Chinese medicinal preparation |
ISSN号 | 0731-7085 |
DOI | 10.1016/j.jpba.2005.10.021 |
文献子类 | Article |
英文摘要 | A high-performance liquid chromatographic method was applied to the determination of danshensu, protocatechuic aldehyde, rosmarinic acid, lithospermic acid, salvianolic acid B and salvianolic acid A in the roots of Salvia miltiorrhiza and four related traditional Chinese medicinal preparations. The six phenolic acids were simultaneously analyzed with a Zorbax Extend C-18 column by gradient elution using 0.026% (v/v) phosphoric acid and acetonitrile as the mobile phase. The flow rate was 1 ml min(-1), and detection wavelength was set at 288 mn. The recovery of the method was in the range of 95.1-104.8%, and all the compounds showed good linearity (r > 0.9997) in a relatively wide concentration range. This assay was successfully applied to the determination of six major phenolic acids in 32 samples. The results indicated that the developed HPLC assay could be readily utilized as a quality control method for S. miltiorrhiza and its related traditional Chinese medicinal preparations. (c) 2005 Elsevier B.V. All rights reserved. |
WOS关键词 | PERFORMANCE LIQUID-CHROMATOGRAPHY ; ROSMARINIC ACID ; RATS ; EXTRACTS ; DANSHEN ; CELLS ; RADIX |
WOS研究方向 | Chemistry ; Pharmacology & Pharmacy |
语种 | 英语 |
WOS记录号 | WOS:000236655100006 |
出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
源URL | [http://119.78.100.183/handle/2S10ELR8/273618] ![]() |
专题 | 上海中药现代化研究中心 |
通讯作者 | Guo, DA |
作者单位 | 1.Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100083, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Biol Sci, Shanghai Inst Mat Med, Shanghai Res Ctr TCM Modernisat, Shanghai 201203, Peoples R China |
推荐引用方式 GB/T 7714 | Liu, AH,Li, L,Xu, M,et al. Simultaneous quantification of six major phenolic acids in the roots of Salvia miltiorrhiza and four related traditional Chinese medicinal preparations by HPLC-DAD method[J]. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,2006,41(1):48-56. |
APA | Liu, AH,Li, L,Xu, M,Lin, YH,Guo, HZ,&Guo, DA.(2006).Simultaneous quantification of six major phenolic acids in the roots of Salvia miltiorrhiza and four related traditional Chinese medicinal preparations by HPLC-DAD method.JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,41(1),48-56. |
MLA | Liu, AH,et al."Simultaneous quantification of six major phenolic acids in the roots of Salvia miltiorrhiza and four related traditional Chinese medicinal preparations by HPLC-DAD method".JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS 41.1(2006):48-56. |
入库方式: OAI收割
来源:上海药物研究所
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