中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Simultaneous quantification of six major phenolic acids in the roots of Salvia miltiorrhiza and four related traditional Chinese medicinal preparations by HPLC-DAD method

文献类型:期刊论文

作者Liu, AH; Li, L; Xu, M; Lin, YH; Guo, HZ; Guo, DA
刊名JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
出版日期2006-04-11
卷号41期号:1页码:48-56
关键词RP-HPLC Salvia miltiorrhiza phenolic acid traditional Chinese medicinal preparation
ISSN号0731-7085
DOI10.1016/j.jpba.2005.10.021
文献子类Article
英文摘要A high-performance liquid chromatographic method was applied to the determination of danshensu, protocatechuic aldehyde, rosmarinic acid, lithospermic acid, salvianolic acid B and salvianolic acid A in the roots of Salvia miltiorrhiza and four related traditional Chinese medicinal preparations. The six phenolic acids were simultaneously analyzed with a Zorbax Extend C-18 column by gradient elution using 0.026% (v/v) phosphoric acid and acetonitrile as the mobile phase. The flow rate was 1 ml min(-1), and detection wavelength was set at 288 mn. The recovery of the method was in the range of 95.1-104.8%, and all the compounds showed good linearity (r > 0.9997) in a relatively wide concentration range. This assay was successfully applied to the determination of six major phenolic acids in 32 samples. The results indicated that the developed HPLC assay could be readily utilized as a quality control method for S. miltiorrhiza and its related traditional Chinese medicinal preparations. (c) 2005 Elsevier B.V. All rights reserved.
WOS关键词PERFORMANCE LIQUID-CHROMATOGRAPHY ; ROSMARINIC ACID ; RATS ; EXTRACTS ; DANSHEN ; CELLS ; RADIX
WOS研究方向Chemistry ; Pharmacology & Pharmacy
语种英语
WOS记录号WOS:000236655100006
出版者PERGAMON-ELSEVIER SCIENCE LTD
源URL[http://119.78.100.183/handle/2S10ELR8/273618]  
专题上海中药现代化研究中心
通讯作者Guo, DA
作者单位1.Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100083, Peoples R China
2.Chinese Acad Sci, Shanghai Inst Biol Sci, Shanghai Inst Mat Med, Shanghai Res Ctr TCM Modernisat, Shanghai 201203, Peoples R China
推荐引用方式
GB/T 7714
Liu, AH,Li, L,Xu, M,et al. Simultaneous quantification of six major phenolic acids in the roots of Salvia miltiorrhiza and four related traditional Chinese medicinal preparations by HPLC-DAD method[J]. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,2006,41(1):48-56.
APA Liu, AH,Li, L,Xu, M,Lin, YH,Guo, HZ,&Guo, DA.(2006).Simultaneous quantification of six major phenolic acids in the roots of Salvia miltiorrhiza and four related traditional Chinese medicinal preparations by HPLC-DAD method.JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,41(1),48-56.
MLA Liu, AH,et al."Simultaneous quantification of six major phenolic acids in the roots of Salvia miltiorrhiza and four related traditional Chinese medicinal preparations by HPLC-DAD method".JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS 41.1(2006):48-56.

入库方式: OAI收割

来源:上海药物研究所

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