PTP1-B inhibitors from Saussrurea Lappa
文献类型：期刊论文
| 作者 | Li, S; An, TY; Li, J ; Shen, Q; Lou, FC; Hu, LH
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| 刊名 | JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
 |
| 出版日期 | 2006-04 |
| 卷号 | 8期号:3页码:281-286 |
| 关键词 | Saussurea lappa PTP1B inhibitors 1,5-dihydroxypinoresinol-4 '-O-beta-D-glucopyranoside |
| ISSN号 | 1028-6020 |
| DOI | 10.1080/10286020412331286434 |
| 文献子类 | Article |
| 英文摘要 | A new lignan glycoside, named 1,5-dihydroxypinoresinol-4'-O-beta-D-glueopyranoside (1), has been isolated from the EtOH extract of the roots of Saussurea lappa, together with twenty known compounds: (+)-1-hydroxypinoresinol-1-O-beta-D-glucopyranoside (2), fraxiresinol-4'-O-beta-D-glucopyranoside (3), (-)-olivil-4 ''-O-beta-D-gucopyranoside (4), 4-allyl-2,6-dimethoxybenzene-1-O-beta-D-glucopyranoside, syringin, costunolide-15-O-beta-D-glucopyranoside, chlorogenic acid, aloe-emodin-8-O-beta-D-glucopyranoside (5), rhein-8-O-beta-D-glucopyranoside (6), chrysophanol (7), emodin, dehydrocostus lactone, costunolide, P-costic acid, reynosin, arbusculin A, a-cyclocostunolide, P-cyclocostunolide, santamarine and magnolialide. Three anthraquinones (5-7) showed moderate bioactivity against human Protein Tyrosine Phosphatase 1B (hPTPIB) in vitro. |
| WOS关键词 | SAUSSUREA-LAPPA ; COSTUNOLIDE ; LIGNANS ; ACID ; SESQUITERPENES ; LACTONE ; PROTEIN ; ROOTS |
| WOS研究方向 | Plant Sciences ; Chemistry ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000238349600013 |
| 出版者 | TAYLOR & FRANCIS LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/273628]  |
| 专题 | 上海中药现代化研究中心 |
| 通讯作者 | Hu, LH |
| 作者单位 | 1.China Pharmaceut Univ, Dept Phytochem, Nanjing 210038, Peoples R China 2.Chinese Acad Sci, Inst Biol Sci, Shanghai Inst Mat Med, Chinese Natl Ctr Drug Screening, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, S,An, TY,Li, J,et al. PTP1-B inhibitors from Saussrurea Lappa[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2006,8(3):281-286. |
| APA | Li, S,An, TY,Li, J,Shen, Q,Lou, FC,&Hu, LH.(2006).PTP1-B inhibitors from Saussrurea Lappa.JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,8(3),281-286. |
| MLA | Li, S,et al."PTP1-B inhibitors from Saussrurea Lappa".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 8.3(2006):281-286. |
入库方式： OAI收割
来源：上海药物研究所
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