Synthesis and peptidyl-prolyl isomerase inhibitory activity of quinoxalines as ligands of cyclophilin A
文献类型：期刊论文
| 作者 | Wang, F; Chen, J ; Liu, XJ; Shen, X; He, XC; Jiang, HL; Bai, DL
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| 刊名 | CHEMICAL & PHARMACEUTICAL BULLETIN
 |
| 出版日期 | 2006-03 |
| 卷号 | 54期号:3页码:372-376 |
| 关键词 | quinoxaline peptidyl-prolyl isomerase inhibitory activity cyclophilin A ligand |
| ISSN号 | 0009-2363 |
| DOI | 10.1248/cpb.54.372 |
| 文献子类 | Article |
| 英文摘要 | In search of small molecule compounds as the ligands of cyclophilin A, a series of quinoxalines were prepared, and their K-d values of cyclophilin A and IC50 values for peptidyl-prolyl isomerase activity of cyclophilin A were tested. The results suggest that some quinoxalines are promising ligands of cyclophilin A. |
| WOS关键词 | CIS-TRANS ISOMERASE ; BINDING-PROTEIN ; CYCLOSPORIN-A ; ANTAGONISTS ; POTENT ; DOMAIN |
| WOS研究方向 | Pharmacology & Pharmacy ; Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000236227000019 |
| 出版者 | PHARMACEUTICAL SOC JAPAN |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/273658]  |
| 专题 | 院士及顾问专家 |
| 通讯作者 | Bai, DL |
| 作者单位 | Chinese Acad Sci, Shanghai Inst Biol Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, F,Chen, J,Liu, XJ,et al. Synthesis and peptidyl-prolyl isomerase inhibitory activity of quinoxalines as ligands of cyclophilin A[J]. CHEMICAL & PHARMACEUTICAL BULLETIN,2006,54(3):372-376. |
| APA | Wang, F.,Chen, J.,Liu, XJ.,Shen, X.,He, XC.,...&Bai, DL.(2006).Synthesis and peptidyl-prolyl isomerase inhibitory activity of quinoxalines as ligands of cyclophilin A.CHEMICAL & PHARMACEUTICAL BULLETIN,54(3),372-376. |
| MLA | Wang, F,et al."Synthesis and peptidyl-prolyl isomerase inhibitory activity of quinoxalines as ligands of cyclophilin A".CHEMICAL & PHARMACEUTICAL BULLETIN 54.3(2006):372-376. |
入库方式： OAI收割
来源：上海药物研究所
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