An improved synthetic method of saquinavir
文献类型：期刊论文
| 作者 | Yang, QG; He, XC; Lei, LJ; Zhou, QT; Bai, DL
|
| 刊名 | CHEMICAL RESEARCH IN CHINESE UNIVERSITIES
 |
| 出版日期 | 2006-01 |
| 卷号 | 22期号:1页码:51-55 |
| 关键词 | HIV protease inhibitor saquinavir synthesis |
| ISSN号 | 1005-9040 |
| DOI | 10.1016/S1005-9040(06)60044-5 |
| 文献子类 | Article |
| 英文摘要 | An improved synthetic method of saquinavir, an HIV protease inhibitor, is described. In comparison with the methods in the reported works, the improved procedures had several advantages, such as less expensive agents, shorter reaction time, and a smaller amount of the solvent needed. To measure the optical purities of the products, the intermediates were determined by means of chiral HPLC. Some of the intermediates can also be used for the preparation of new protease inhibitors. |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| CSCD记录号 | CSCD:2659489 |
| WOS记录号 | WOS:000235181400013 |
| 出版者 | HIGHER EDUCATION PRESS |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/273701]  |
| 专题 | 院士及顾问专家 |
| 通讯作者 | Bai, DL |
| 作者单位 | Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai Inst Biol Sci, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yang, QG,He, XC,Lei, LJ,et al. An improved synthetic method of saquinavir[J]. CHEMICAL RESEARCH IN CHINESE UNIVERSITIES,2006,22(1):51-55. |
| APA | Yang, QG,He, XC,Lei, LJ,Zhou, QT,&Bai, DL.(2006).An improved synthetic method of saquinavir.CHEMICAL RESEARCH IN CHINESE UNIVERSITIES,22(1),51-55. |
| MLA | Yang, QG,et al."An improved synthetic method of saquinavir".CHEMICAL RESEARCH IN CHINESE UNIVERSITIES 22.1(2006):51-55. |
入库方式： OAI收割
来源：上海药物研究所
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