Identification and Structural Characterization of Acylgluconic Acids, Flavonol Glycosides, Limonoids and Alkaloids from the Fruits of Evodia Rutaecarpa by High Performance Liquid Chromatography Coupled to Electrospray Ionization and Quadrupole Time-of-Flight Mass Spectrometry
文献类型：期刊论文
| 作者 | Ling, Yun1; Hu, Pei1,2; Zhang, Lifang1; Jin, Hongguang1; Chen, Jian1; Tao, Zhi1; Huang, Ling1; Ren, Ruoyu1 |
| 刊名 | JOURNAL OF CHROMATOGRAPHIC SCIENCE
 |
| 出版日期 | 2016-10 |
| 卷号 | 54期号:9页码:1593-1604 |
| ISSN号 | 0021-9665 |
| DOI | 10.1093/chromsci/bmw109 |
| 文献子类 | Article |
| 英文摘要 | The dried fruit of Evodia rutaecarpa (Juss.) Benth. (ER) is a well-known traditional Chinese medicine and has been used in treatment of headache, abdominal pain, migraine, chill limbs, diarrhea, nausea, hyperbaropathy, dysmenorrheal and postpartum hemorrhage. In this work, a comprehensive characterization of chemical constituents in ER extract is carried out by high performance liquid chromatography coupled to electrospray ionization and quadrupole time-of-flight mass spectrometry. The increased power of higher mass resolution and exact mass measurements for precursor and fragment ions lead to detection of 3 acylgluconic acids, 3 flavonol glycosides, 6 limonoids and 24 alkaloids in ER, of which 6 quinolone alkaloids has not been reported previously to our best knowledge. This research enriches our knowledge of chemical constituents of ER and provides a reliable guide for further pharmacology and active mechanism study on this herb. |
| WOS关键词 | QUINOLONE ALKALOIDS |
| 资助项目 | Educational Department of Jiangxi Province of China[GJJ151075] ; Natural Science Foundation of Jiangxi Province of China[20161BAB215194] ; Jiujiang University[8500259] |
| WOS研究方向 | Biochemistry & Molecular Biology ; Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000389139300018 |
| 出版者 | OXFORD UNIV PRESS INC |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/275871]  |
| 专题 | 上海中药现代化研究中心 |
| 通讯作者 | Ling, Yun |
| 作者单位 | 1.Jiujiang Univ, Dept Pharmaceut & Life Sci, Jiujiang 332005, Peoples R China; 2.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Ling, Yun,Hu, Pei,Zhang, Lifang,et al. Identification and Structural Characterization of Acylgluconic Acids, Flavonol Glycosides, Limonoids and Alkaloids from the Fruits of Evodia Rutaecarpa by High Performance Liquid Chromatography Coupled to Electrospray Ionization and Quadrupole Time-of-Flight Mass Spectrometry[J]. JOURNAL OF CHROMATOGRAPHIC SCIENCE,2016,54(9):1593-1604. |
| APA | Ling, Yun.,Hu, Pei.,Zhang, Lifang.,Jin, Hongguang.,Chen, Jian.,...&Ren, Ruoyu.(2016).Identification and Structural Characterization of Acylgluconic Acids, Flavonol Glycosides, Limonoids and Alkaloids from the Fruits of Evodia Rutaecarpa by High Performance Liquid Chromatography Coupled to Electrospray Ionization and Quadrupole Time-of-Flight Mass Spectrometry.JOURNAL OF CHROMATOGRAPHIC SCIENCE,54(9),1593-1604. |
| MLA | Ling, Yun,et al."Identification and Structural Characterization of Acylgluconic Acids, Flavonol Glycosides, Limonoids and Alkaloids from the Fruits of Evodia Rutaecarpa by High Performance Liquid Chromatography Coupled to Electrospray Ionization and Quadrupole Time-of-Flight Mass Spectrometry".JOURNAL OF CHROMATOGRAPHIC SCIENCE 54.9(2016):1593-1604. |
入库方式： OAI收割
来源：上海药物研究所
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