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Biotransformation of patchoulol by Cunninghamella echinulata var. elegans

文献类型：期刊论文

作者Xu, Fangfang3; Liao, Kangsheng3; Liu, Yuhong2; Zhang, Zhenbiao2; Guo, Dean1; Su, Ziren2; Liu, Bo3
刊名FITOTERAPIA
出版日期2016-03
卷号109页码:201-205
关键词Biotransformation Patchoulol Cunninghamella echinulata var. elegans X-ray crystallography
ISSN号0367-326X
DOI10.1016/j.fitote.2016.01.001
文献子类Article
英文摘要Biocatalysis of patchoulol (PA) was performed by the fungus Cunninghamella echinulata var. elegans. Eight metabolites (1-8) including four new compounds were obtained, and their structures were elucidated as (5R,8S)-5,8 dihydroxypatchoulol (1), (5R*,9R*)-5,9 dihydroxypatchoulol (2), (6S*, 9S*) -6,9 dihydroxypatchoulol (3), and (4R*) -4 hydroxypatchoulol (4) by spectroscopic analysis. The absolute configuration of 1 was determined by single crystal X-ray diffraction. (C) 2016 Elsevier B.V. All rights reserved.
WOS关键词POGOSTEMONIS HERBA ; ARTEMISININ
资助项目National Natural Science Foundation of China[81202398] ; Specific Research Construction Project of National Clinical Research Base of TCM[JDZX2012010]
WOS研究方向Pharmacology & Pharmacy
语种英语
WOS记录号WOS:000372685400032
出版者ELSEVIER SCIENCE BV
源URL[http://119.78.100.183/handle/2S10ELR8/276116]  
专题上海中药现代化研究中心
通讯作者Guo, Dean; Su, Ziren; Liu, Bo
作者单位1.Chinese Acad Sci, Natl Engn Lab TCM Standardizat Technol, Shanghai Res Ctr Modernizat Tradit Chinese Med, Shanghai Inst Mat Med, 501 Haike Rd, Shanghai 201203, Peoples R China
2.Guangzhou Univ Chinese Med, Coll Chinese Med, Guangzhou 510006, Guangdong, Peoples R China;
3.Guangzhou Univ Chinese Med, Affiliated Hosp 2, Guangdong Prov Acad Chinese Med Sci, Guangzhou 510006, Guangdong, Peoples R China;
推荐引用方式
GB/T 7714		 Xu, Fangfang,Liao, Kangsheng,Liu, Yuhong,et al. Biotransformation of patchoulol by Cunninghamella echinulata var. elegans[J]. FITOTERAPIA,2016,109:201-205.
APA Xu, Fangfang.,Liao, Kangsheng.,Liu, Yuhong.,Zhang, Zhenbiao.,Guo, Dean.,...&Liu, Bo.(2016).Biotransformation of patchoulol by Cunninghamella echinulata var. elegans.FITOTERAPIA,109,201-205.
MLA Xu, Fangfang,et al."Biotransformation of patchoulol by Cunninghamella echinulata var. elegans".FITOTERAPIA 109(2016):201-205.

入库方式： OAI收割

来源：上海药物研究所

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