Qualitative and quantitative analysis of the major constituents in Acorus tatarinowii Schott by HPLC/ESI-QTOF-MS/MS
文献类型：期刊论文
| 作者 | Zhang, Feng1; Qi, Peng1; Xue, Rui1; Li, Zhixiong1 ; Zhu, Kaicheng1; Wan, Ping2; Huang, Chenggang1
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| 刊名 | BIOMEDICAL CHROMATOGRAPHY
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| 出版日期 | 2015-06 |
| 卷号 | 29期号:6页码:890-901 |
| 关键词 | HPLC ESI-QTOF-MS MS Acorus tatarinowii Schott identification quantification |
| ISSN号 | 0269-3879 |
| DOI | 10.1002/bmc.3371 |
| 文献子类 | Article |
| 英文摘要 | Acorus tatarinowii Schott (ATS) is a well-known traditional Chinese medicine (TCM) for the treatment of epilepsy, amnesia and insomnia. In this study, a methodology utilizing high-performance liquid chromatography (HPLC) coupled with electrospray ionization quadrupole time-of-flight mass spectrometry (ESI-QTOF-MS/MS) was established for the separation and structural identification of the major chemical constituents in ATS for the first time. Overall, 46 major constituents including flavonoid glycosides, phenylpropane derivatives, amides and lignans were identified or tentatively characterized. Seven major constituents, including four phenylpropane derivatives and three lignans, were further quantified as marker substances, which showed good linearity within the test ranges. These results indicated that the developed quantitative method was linear, sensitive, and precise for quality control of ATS. Copyright (c) 2014 John Wiley & Sons, Ltd. |
| WOS关键词 | MASS-SPECTROMETRY ; ESSENTIAL OIL ; CALAMUS ; WATER ; SESQUITERPENOIDS ; PHARMACEUTICALS ; COMPONENTS ; ASARONE |
| 资助项目 | National Science and Technology Major Project 'Key New Drug Creation and Manufacturing Program', China[2012ZX09301001] ; Science and Technology Commission of Shanghai Municipality, China[13401900600] |
| WOS研究方向 | Biochemistry & Molecular Biology ; Chemistry ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000354999500009 |
| 出版者 | WILEY-BLACKWELL |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/276515]  |
| 专题 | 上海中药现代化研究中心 |
| 通讯作者 | Huang, Chenggang |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China; 2.Shanghai Normal Univ, Life & Environm Sci Coll, Shanghai 200234, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Feng,Qi, Peng,Xue, Rui,et al. Qualitative and quantitative analysis of the major constituents in Acorus tatarinowii Schott by HPLC/ESI-QTOF-MS/MS[J]. BIOMEDICAL CHROMATOGRAPHY,2015,29(6):890-901. |
| APA | Zhang, Feng.,Qi, Peng.,Xue, Rui.,Li, Zhixiong.,Zhu, Kaicheng.,...&Huang, Chenggang.(2015).Qualitative and quantitative analysis of the major constituents in Acorus tatarinowii Schott by HPLC/ESI-QTOF-MS/MS.BIOMEDICAL CHROMATOGRAPHY,29(6),890-901. |
| MLA | Zhang, Feng,et al."Qualitative and quantitative analysis of the major constituents in Acorus tatarinowii Schott by HPLC/ESI-QTOF-MS/MS".BIOMEDICAL CHROMATOGRAPHY 29.6(2015):890-901. |
入库方式： OAI收割
来源：上海药物研究所
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