A coumarin lignanoid from the stems of Kadsura heteroclita
文献类型：期刊论文
| 作者 | Su, Wei3,4; Zhao, Jianping5; Yang, Min6; Yan, Hui-Wen7; Pang, Tao1; Chen, Sheng-Huang3,4; Huang, Hui-Yong3,4; Zhang, Shui-Han3,4; Ma, Xiao-Chi2; Guo, De-An6
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| 刊名 | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
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| 出版日期 | 2015-04-01 |
| 卷号 | 25期号:7页码:1506-1508 |
| ISSN号 | 0960-894X |
| 关键词 | Coumarin lignoid Coumarinlignan Kadsura heteroclita Anti-HBV activity |
| DOI | 10.1016/j.bmcl.2015.02.022 |
| 文献子类 | Article |
| 英文摘要 | Coumarinlignan (1), possessing a unique coumarin-containing lignan skeleton, was isolated from the stems of Kadsura heteroclita. Its structure and absolute configuration were determined by spectroscopic techniques, especially 2D NMR and X-ray crystallographic data analyses. The proposed biosynthetic pathway is discussed. This new compound showed good anti-HBV activity against HBeAg and HBsAg, and moderate anti-fibrotic and neuroprotective activities. (C) 2015 Elsevier Ltd. All rights reserved. |
| WOS关键词 | TRITERPENOIDS ; COCCINEA ; PHILIPPINENSIS ; HOMOLIGNANS |
| 资助项目 | National Natural Science Foundation of China[81374062] ; Hunan Administration of TCM Research Key Project[201215] ; Ministry of Education of Overseas Returnees Start-up Find for Scientific Research[2013693] ; Specialized Research Fund for the Doctoral Program of Higher Education of China[20134323110004] ; Hunan Science and Research Institutions Technological Innovation and Development Project[2012TF1005] ; Hunan Science & Technology Bureau Science & Technology Plan[2014SK4037] |
| WOS研究方向 | Pharmacology & Pharmacy ; Chemistry |
| 语种 | 英语 |
| 出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
| WOS记录号 | WOS:000351688700028 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/276590]  |
| 专题 | 上海中药现代化研究中心 |
| 通讯作者 | Wang, Wei |
| 作者单位 | 1.China Pharmaceut Univ, New Drug Screening Ctr, State Key Lab Nat Med, Nanjing 210009, Jiangsu, Peoples R China; 2.Dalian Med Univ, Coll Pharm, Dalian 116044, Peoples R China 3.Hunan Univ Chinese Med, Sch Pharm, Sino Luxemburg TCM Res Ctr, TCM, Changsha 410208, Hunan, Peoples R China; 4.Hunan Univ Chinese Med, Sch Pharm, Sino Luxemburg TCM Res Ctr, Ethnomed Innovat & Dev Lab, Changsha 410208, Hunan, Peoples R China; 5.Univ Mississippi, Natl Ctr Nat Prod Res, Pharmaceut Sci Res Inst, University, MS 38677 USA; 6.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai Res Ctr Modernizat Tradit Chinese Med, Natl Engn Lab TCM Standardizat Technol, Shanghai 201203, Peoples R China; 7.Cent S Univ, Sch Life Sci, Changsha 410013, Peoples R China; |
| 推荐引用方式 GB/T 7714 | Su, Wei,Zhao, Jianping,Yang, Min,et al. A coumarin lignanoid from the stems of Kadsura heteroclita[J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,2015,25(7):1506-1508. |
| APA | Su, Wei.,Zhao, Jianping.,Yang, Min.,Yan, Hui-Wen.,Pang, Tao.,...&Wang, Wei.(2015).A coumarin lignanoid from the stems of Kadsura heteroclita.BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,25(7),1506-1508. |
| MLA | Su, Wei,et al."A coumarin lignanoid from the stems of Kadsura heteroclita".BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 25.7(2015):1506-1508. |
入库方式： OAI收割
来源：上海药物研究所
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