Ullmann-type C-N coupling reaction catalyzed by CuI/metformin
文献类型：期刊论文
| 作者 | Zhang, Chao1; Zhan, Zhajun1; Lei, Min2 ; Hu, Lihong1,2
|
| 刊名 | TETRAHEDRON
 |
| 出版日期 | 2014-11-18 |
| 卷号 | 70期号:46页码:8817-8821 |
| 关键词 | Amine Aryl halide C-N coupling reaction Metformin Ullmann-type reaction |
| ISSN号 | 0040-4020 |
| DOI | 10.1016/j.tet.2014.10.014 |
| 文献子类 | Article |
| 英文摘要 | A facile and efficient method for Ullmann-type C-N coupling reaction of amine and aryl halide catalyzed by CuI/metformin in EtOH is described. The advantages of this method are the use of an inexpensive and readily available catalyst and ligand, easy workup, shorter reaction time, improved yields, and the use of green solvent. Furthermore, this procedure is applied successfully for the modification of natural products, such as Vindoline and Tabersonin. (C) 2014 Elsevier Ltd. All rights reserved. |
| WOS关键词 | ARYL IODIDES ; HIGHLY EFFICIENT ; ALIPHATIC-AMINES ; ROOM-TEMPERATURE ; ALKYLAMINES ; ARYLATION ; LIGAND ; PHOSPHORAMIDITE ; IODOBENZENE ; BROMIDES |
| 资助项目 | National Natural Science Foundation of China[30925040] ; National Natural Science Foundation of China[81102329] ; National Natural Science Foundation of China[81273397] ; Chinese National Science & Technology Major Project 'Key New Drug Creation and Manufacturing Program'[2013ZX09508104] ; Chinese National Science & Technology Major Project 'Key New Drug Creation and Manufacturing Program'[2012ZX09301001-001] ; Chinese National Science & Technology Major Project 'Key New Drug Creation and Manufacturing Program'[2011ZX09307-002-03] ; Science Foundation of Shanghai[12XD1405700] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000344204700002 |
| 出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/276832]  |
| 专题 | 上海中药现代化研究中心 |
| 通讯作者 | Lei, Min |
| 作者单位 | 1.Zhejiang Univ Technol, Coll Phanaceut Sci, Hangzhou 310014, Zhejiang, Peoples R China; 2.Shanghai Inst Mat Med, Shanghai Res Ctr Modernizat Tradit Chinese Med, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Chao,Zhan, Zhajun,Lei, Min,et al. Ullmann-type C-N coupling reaction catalyzed by CuI/metformin[J]. TETRAHEDRON,2014,70(46):8817-8821. |
| APA | Zhang, Chao,Zhan, Zhajun,Lei, Min,&Hu, Lihong.(2014).Ullmann-type C-N coupling reaction catalyzed by CuI/metformin.TETRAHEDRON,70(46),8817-8821. |
| MLA | Zhang, Chao,et al."Ullmann-type C-N coupling reaction catalyzed by CuI/metformin".TETRAHEDRON 70.46(2014):8817-8821. |
入库方式： OAI收割
来源：上海药物研究所
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