中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Saponins in the genus Panax L. (Araliaceae): A systematic review of their chemical diversity

文献类型:期刊论文

作者Yang, Wen-zhi2; Hu, Ying1; Wu, Wan-ying2; Ye, Min1; Guo, De-an2
刊名PHYTOCHEMISTRY
出版日期2014-10
卷号106页码:7-24
关键词Panax genus Panax ginseng Panax quinquefolius Panax notoginseng Araliaceae Saponins Chemical diversity Subtype classification
ISSN号0031-9422
DOI10.1016/j.phytochem.2014.07.012
文献子类Review
英文摘要The Panax genus is a crucial source of natural medicines that has benefited human health for a long time. Three valuable medicinal herbs, namely Panax ginseng, Panax quinquefolius, and Panax notoginseng, have received considerable interest due to their extensive application in clinical therapy, healthcare products, and as foods and food additives world-wide. Panax species are known to contain abundant levels of saponins, also dubbed ginsenosides, which refer to a series of dammarane or oleanane type triterpenoid glycosides. These saponins exhibit modulatory effects to the central nervous system and beneficial effects to patients suffering from cardiovascular diseases, and also have anti-diabetic and anti-tumor properties. To the end of 2012, at least 289 saponins were reported from eleven different Panax species. This comprehensive review describes the advances in the phytochemistry of the genus Panax for the period 1963-2012, based on the 134 cited references. The reported saponins can be classified into protopanaxadiol, protopanaxatriol, octillol, oleanolic acid, C17 side-chain varied, and miscellaneous subtypes, according to structural differences in sapogenins. The investigational history of Panax is also reviewed, with special attention being paid to the structural features of the six different subtypes, together with their H-1 and C-13 NMR spectroscopic characteristics which are useful for determining their structures and absolute configuration. (C) 2014 Elsevier Ltd. All rights reserved.
WOS关键词DAMMARANE-TYPE SAPONINS ; KOREAN RED GINSENG ; HEAT-PROCESSED GINSENG ; ORIENTAL PLANT DRUGS ; F H. CHEN ; FLOWER-BUDS ; TRITERPENE SAPONINS ; QUINQUEFOLIUM-L ; CA MEYER ; BIOACTIVE SAPONINS
资助项目Program for New Century Excellent Talents in University from China Ministry of Education[BMU20110269]
WOS研究方向Biochemistry & Molecular Biology ; Plant Sciences
语种英语
WOS记录号WOS:000342258600001
出版者PERGAMON-ELSEVIER SCIENCE LTD
源URL[http://119.78.100.183/handle/2S10ELR8/276890]  
专题上海中药现代化研究中心
通讯作者Ye, Min
作者单位1.Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China
2.Chinese Acad Sci, Shanghai Res Ctr Modernizat Tradit Chinese Med, Natl Engn Lab TCM Standardizat Technol, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China;
推荐引用方式
GB/T 7714
Yang, Wen-zhi,Hu, Ying,Wu, Wan-ying,et al. Saponins in the genus Panax L. (Araliaceae): A systematic review of their chemical diversity[J]. PHYTOCHEMISTRY,2014,106:7-24.
APA Yang, Wen-zhi,Hu, Ying,Wu, Wan-ying,Ye, Min,&Guo, De-an.(2014).Saponins in the genus Panax L. (Araliaceae): A systematic review of their chemical diversity.PHYTOCHEMISTRY,106,7-24.
MLA Yang, Wen-zhi,et al."Saponins in the genus Panax L. (Araliaceae): A systematic review of their chemical diversity".PHYTOCHEMISTRY 106(2014):7-24.

入库方式: OAI收割

来源:上海药物研究所

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