SIMPLE AND EFFICIENT METHOD FOR THE SYNTHESIS OF 1-((ARYL)(2-OXOINDOLIN-3-YL-)METHYL)UREA AND 1-((ARYL)(2-OXOINDOLIN-3-YL-)METHYL)THIOUREA DERIVATIVES
文献类型：期刊论文
| 作者 | Yan, Jianming; Lei, Min ; Hu, Lihong
|
| 刊名 | SYNTHETIC COMMUNICATIONS
 |
| 出版日期 | 2014-01-02 |
| 卷号 | 44期号:1页码:127-132 |
| 关键词 | Green chemistry 2-indolinone multicomponent reaction p-TsOH |
| ISSN号 | 0039-7911 |
| DOI | 10.1080/00397911.2013.794362 |
| 文献子类 | Article |
| 英文摘要 | A number of new1-((aryl)(2-oxoindolin-3-yl)methyl)urea and 1-((aryl)(2-oxoindolin-3-yl)methyl)thiourea derivatives have been prepared by simply combining 2-indolinone, aromatic aldehyde, and urea or thiourea in the presence of p-TsOH in EtOH. This new methodology affords the title compounds in good yields and without the use of chromatography. [Supplementary materials are available for this article. Go to the publisher's online edition of Synthetic Communications (R) for the following free supplemental resource(s): Full experimental and spectral details.] |
| WOS关键词 | UREAS |
| 资助项目 | Chinese National Science and Technology Major Project Key New Drug Creation and Manufacturing Program[2009ZX09301-001] ; Chinese National Science and Technology Major Project Key New Drug Creation and Manufacturing Program[2009ZX09102-022] ; National Natural Science Foundation of China[30925040] ; National Natural Science Foundation of China[81102329] ; National Natural Science Foundation of China[90713046] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000325514400013 |
| 出版者 | TAYLOR & FRANCIS INC |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/277240]  |
| 专题 | 上海中药现代化研究中心 |
| 通讯作者 | Lei, Min |
| 作者单位 | Shanghai Inst Mat Med, Shanghai Res Ctr Modernizat Tradit Chinese Med, Shanghai, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yan, Jianming,Lei, Min,Hu, Lihong. SIMPLE AND EFFICIENT METHOD FOR THE SYNTHESIS OF 1-((ARYL)(2-OXOINDOLIN-3-YL-)METHYL)UREA AND 1-((ARYL)(2-OXOINDOLIN-3-YL-)METHYL)THIOUREA DERIVATIVES[J]. SYNTHETIC COMMUNICATIONS,2014,44(1):127-132. |
| APA | Yan, Jianming,Lei, Min,&Hu, Lihong.(2014).SIMPLE AND EFFICIENT METHOD FOR THE SYNTHESIS OF 1-((ARYL)(2-OXOINDOLIN-3-YL-)METHYL)UREA AND 1-((ARYL)(2-OXOINDOLIN-3-YL-)METHYL)THIOUREA DERIVATIVES.SYNTHETIC COMMUNICATIONS,44(1),127-132. |
| MLA | Yan, Jianming,et al."SIMPLE AND EFFICIENT METHOD FOR THE SYNTHESIS OF 1-((ARYL)(2-OXOINDOLIN-3-YL-)METHYL)UREA AND 1-((ARYL)(2-OXOINDOLIN-3-YL-)METHYL)THIOUREA DERIVATIVES".SYNTHETIC COMMUNICATIONS 44.1(2014):127-132. |
入库方式： OAI收割
来源：上海药物研究所
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