Cardenolides from the bark of Calotropis gigantea
文献类型：期刊论文
| 作者 | Pham Van Khang1; Zhang, Zhong-Guo1; Meng, Yu-Hui2; Guo, De-An2 ; Liu, Xuan2; Hu, Li-Hong1,2; Ma, Lei1
|
| 刊名 | NATURAL PRODUCT RESEARCH
 |
| 出版日期 | 2014 |
| 卷号 | 28期号:15页码:1191-1196 |
| 关键词 | Calotropis gigantea cardenolide Asclepiadaceae A459 HeLa |
| ISSN号 | 1478-6419 |
| DOI | 10.1080/14786419.2014.909419 |
| 文献子类 | Article |
| 英文摘要 | Three new cardenolides (1-3) were isolated from the 90% ethanolic extract of the bark of a wild-type Calotropis gigantea. Their structures were determined by using NMR spectra and LC-MS analysis. Their inhibitory activities were evaluated against non-small cell lung carcinoma (A549) and human cervix epithelial adenocarcinoma (HeLa) cell lines. Compounds 1 and 3 exhibited strong inhibitory effect on two cancer cell lines. |
| WOS关键词 | CYTOTOXIC CARDENOLIDES ; GLYCOSIDES ; LEAVES ; LATEX ; ROOT ; L. |
| 资助项目 | National Natural Science Foundation of China[21002027] ; National Natural Science Foundation of China[30925040] ; Chinese National Science & Technology Major Project "Key New Drug Creation and Manufacturing Program"[2013ZX09508104] ; Chinese National Science & Technology Major Project "Key New Drug Creation and Manufacturing Program"[2012ZX09301001-001] ; Chinese National Science & Technology Major Project "Key New Drug Creation and Manufacturing Program"[2011ZX09307-002-03] ; Fundamental Research Funds for the Central Universities[WY1114026] ; China 111 Project[B07023] |
| WOS研究方向 | Chemistry ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000339097500012 |
| 出版者 | TAYLOR & FRANCIS LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/277278]  |
| 专题 | 上海中药现代化研究中心 |
| 通讯作者 | Ma, Lei |
| 作者单位 | 1.E China Univ Sci & Technol, Shanghai Key Lab New Drug Design, Sch Pharm, Shanghai 200237, Peoples R China; 2.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai Res Ctr Modernizat Tradit Chinese Med, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Pham Van Khang,Zhang, Zhong-Guo,Meng, Yu-Hui,et al. Cardenolides from the bark of Calotropis gigantea[J]. NATURAL PRODUCT RESEARCH,2014,28(15):1191-1196. |
| APA | Pham Van Khang.,Zhang, Zhong-Guo.,Meng, Yu-Hui.,Guo, De-An.,Liu, Xuan.,...&Ma, Lei.(2014).Cardenolides from the bark of Calotropis gigantea.NATURAL PRODUCT RESEARCH,28(15),1191-1196. |
| MLA | Pham Van Khang,et al."Cardenolides from the bark of Calotropis gigantea".NATURAL PRODUCT RESEARCH 28.15(2014):1191-1196. |
入库方式： OAI收割
来源：上海药物研究所
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