Synthesis of 2-substituted-3-(1H-indol-3-yl)-isoindolin-1-one derivatives in water under catalyst-free conditions
文献类型：期刊论文
| 作者 | Chen, Fanglei; Lei, Min ; Hu, Lihong
|
| 刊名 | GREEN CHEMISTRY
 |
| 出版日期 | 2014 |
| 卷号 | 16期号:5页码:2472-2479 |
| ISSN号 | 1463-9262 |
| DOI | 10.1039/c3gc41882k |
| 文献子类 | Article |
| 英文摘要 | A series of 3-(1H-indol-3-yl)isoindolin-1-one derivatives were synthesized by the three-component reaction of a phthalaldehydic acid, primary amine, and 1H-indole in water under catalyst-free conditions. The reaction presented here has several advantages, such as clean, one-pot, and easy handling. The environmentally-friendly features make this procedure a sustainable method for the synthesis of 3-(1H-indol-3-yl)isoindolin-1-ones. |
| WOS关键词 | THIAMINE HYDROCHLORIDE VB1 ; ONE-POT SYNTHESIS ; MULTICOMPONENT REACTIONS ; EFFICIENT PROMOTER |
| 资助项目 | National Natural Science Foundation of China[30925040] ; National Natural Science Foundation of China[81102329] ; National Natural Science Foundation of China[81273397] ; Chinese National Science & Technology Major Project "Key New Drug Creation and Manufacturing Program"[2013ZX09508104] ; Chinese National Science & Technology Major Project "Key New Drug Creation and Manufacturing Program"[2012ZX09301001-001] ; Chinese National Science & Technology Major Project "Key New Drug Creation and Manufacturing Program"[2011ZX09307-002-03] ; Science Foundation of Shanghai[12XD1405700] |
| WOS研究方向 | Chemistry ; Science & Technology - Other Topics |
| 语种 | 英语 |
| WOS记录号 | WOS:000335005200016 |
| 出版者 | ROYAL SOC CHEMISTRY |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/277292]  |
| 专题 | 上海中药现代化研究中心 |
| 通讯作者 | Chen, Fanglei |
| 作者单位 | Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai Res Ctr Modernizat Tradit Chinese Med, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chen, Fanglei,Lei, Min,Hu, Lihong. Synthesis of 2-substituted-3-(1H-indol-3-yl)-isoindolin-1-one derivatives in water under catalyst-free conditions[J]. GREEN CHEMISTRY,2014,16(5):2472-2479. |
| APA | Chen, Fanglei,Lei, Min,&Hu, Lihong.(2014).Synthesis of 2-substituted-3-(1H-indol-3-yl)-isoindolin-1-one derivatives in water under catalyst-free conditions.GREEN CHEMISTRY,16(5),2472-2479. |
| MLA | Chen, Fanglei,et al."Synthesis of 2-substituted-3-(1H-indol-3-yl)-isoindolin-1-one derivatives in water under catalyst-free conditions".GREEN CHEMISTRY 16.5(2014):2472-2479. |
入库方式： OAI收割
来源：上海药物研究所
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