A one-pot synthesis of isoindolin-1-imine derivatives
文献类型：期刊论文
| 作者 | Khangvan Pham2; Zhang, Zhongguo2; Shen, Sida2; Ma, Lei2; Hu, Lihong1,2 |
| 刊名 | TETRAHEDRON
 |
| 出版日期 | 2013-12-23 |
| 卷号 | 69期号:51页码:10933-10939 |
| 关键词 | 2-Cyanobenzaldehyde 4-Hydroxycoumarin Isoindolin-l-imine 4-Hydroxyquinolin-2(1H)-one One-pot reaction |
| ISSN号 | 0040-4020 |
| DOI | 10.1016/j.tet.2013.10.076 |
| 文献子类 | Article |
| 英文摘要 | A one-pot procedure was developed for the synthesis of isoindolin-l-imine derivatives by a simple three-component condensation of 2-cyanobenzaldhyde, ammonium acetate, and 4-hyroxycoumarin derivatives or 1,3-dicarbonyl compounds or 4-hydroxyquinolin-2(1H)-one in ethanol under reflux for 20-60 min with excellent yields. The advantages of this procedure are operational simplicity, excellent yields, and short reactive time, without catalyst, easy workup, and green environmental impact. (C) 2013 Elsevier Ltd. All rights reserved. |
| WOS关键词 | NMDA RECEPTOR ANTAGONISTS ; IN-VIVO ACTIVITY ; 4-HYDROXYCOUMARIN DERIVATIVES ; THIAMINE HYDROCHLORIDE ; GLYCINE SITE ; DICUMAROL ; CATALYST ; BINDING ; AMINO |
| 资助项目 | National Natural Science Foundation of China[21002027] ; National Natural Science Foundation of China[90713046] ; National Natural Science Foundation of China[30925040] ; Fundamental Research Funds for the Central Universities[WY1114026] ; China 111 Project[B07023] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000328808300018 |
| 出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/277328]  |
| 专题 | 上海中药现代化研究中心 |
| 通讯作者 | Ma, Lei |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai Res Ctr Modernizat Tradit Chinese Med, Shanghai 201203, Peoples R China 2.E China Univ Sci & Technol, Sch Pharm, Shanghai Key Lab New Drug Design, Shanghai 200237, Peoples R China; |
| 推荐引用方式 GB/T 7714 | Khangvan Pham,Zhang, Zhongguo,Shen, Sida,et al. A one-pot synthesis of isoindolin-1-imine derivatives[J]. TETRAHEDRON,2013,69(51):10933-10939. |
| APA | Khangvan Pham,Zhang, Zhongguo,Shen, Sida,Ma, Lei,&Hu, Lihong.(2013).A one-pot synthesis of isoindolin-1-imine derivatives.TETRAHEDRON,69(51),10933-10939. |
| MLA | Khangvan Pham,et al."A one-pot synthesis of isoindolin-1-imine derivatives".TETRAHEDRON 69.51(2013):10933-10939. |
入库方式： OAI收割
来源：上海药物研究所
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