A facile protocol for the synthesis of 4-aryl-1,4,7,8-tetrahydro-3,5-dimethyldipyrazolo[3,4-b:4 ',3 '-e]pyridine derivatives by a Hantzsch-type reaction
文献类型：期刊论文
| 作者 | Zhao, Kun1; Lei, Min1 ; Ma, Lei2; Hu, Lihong1
|
| 刊名 | MONATSHEFTE FUR CHEMIE
 |
| 出版日期 | 2011-11 |
| 卷号 | 142期号:11页码:1169-1173 |
| 关键词 | Hantzsch-type reaction Aldehyde 3-Methyl-1H-pyrazol-5(4H)-one Catalyst-free |
| ISSN号 | 0026-9247 |
| DOI | 10.1007/s00706-011-0565-8 |
| 文献子类 | Article |
| 英文摘要 | A facile and efficient protocol is described for the synthesis of 4-aryl-1,4,7,8-tetrahydro-3,5-dimethyldipyrazolo[3,4-b:4',3'-e]pyridine derivatives in good yields by the condensation of 3-methyl-1H-pyrazol-5(4H)-one, aromatic aldehydes, and ammonium acetate under catalyst-free conditions. The advantages of this protocol are operational simplicity, mild reaction conditions, high yields, and little environmental impact. |
| WOS关键词 | ONE-POT SYNTHESIS ; POLYHYDROQUINOLINE DERIVATIVES ; CALCIUM-CHANNEL ; AMBIENT-TEMPERATURE ; SOLVENT-FREE ; 1,4-DIHYDROPYRIDINES ; ANTAGONISTS ; EFFICIENT ; CONDENSATION ; 4-COMPONENT |
| 资助项目 | Chinese National Science and Technology Major Project 'Key New Drug Creation and Manufacturing Program'[2009ZX09301-001] ; Chinese National Science and Technology Major Project 'Key New Drug Creation and Manufacturing Program'[2009ZX09102-022] ; National Natural Science Foundation of China[21002027] ; National Natural Science Foundation of China[90713046] ; National Natural Science Foundation of China[30772638] ; National Natural Science Foundation of China[30925040] ; CAS Foundation[KSCX2-YW-R-179] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000297216100012 |
| 出版者 | SPRINGER WIEN |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/278351]  |
| 专题 | 上海中药现代化研究中心 |
| 通讯作者 | Ma, Lei |
| 作者单位 | 1.Shanghai Inst Mat Med, Shanghai Res Ctr Modernizat Tradit Chinese Med, Shanghai 201203, Peoples R China; 2.E China Univ Sci & Technol, Sch Pharm, Shanghai 200237, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhao, Kun,Lei, Min,Ma, Lei,et al. A facile protocol for the synthesis of 4-aryl-1,4,7,8-tetrahydro-3,5-dimethyldipyrazolo[3,4-b:4 ',3 '-e]pyridine derivatives by a Hantzsch-type reaction[J]. MONATSHEFTE FUR CHEMIE,2011,142(11):1169-1173. |
| APA | Zhao, Kun,Lei, Min,Ma, Lei,&Hu, Lihong.(2011).A facile protocol for the synthesis of 4-aryl-1,4,7,8-tetrahydro-3,5-dimethyldipyrazolo[3,4-b:4 ',3 '-e]pyridine derivatives by a Hantzsch-type reaction.MONATSHEFTE FUR CHEMIE,142(11),1169-1173. |
| MLA | Zhao, Kun,et al."A facile protocol for the synthesis of 4-aryl-1,4,7,8-tetrahydro-3,5-dimethyldipyrazolo[3,4-b:4 ',3 '-e]pyridine derivatives by a Hantzsch-type reaction".MONATSHEFTE FUR CHEMIE 142.11(2011):1169-1173. |
入库方式： OAI收割
来源：上海药物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。