A green, efficient, and rapid procedure for the synthesis of 2-amino-3-cyano-1,4,5,6-tetrahydropyrano[3,2-c]quinolin-5-one derivatives catalyzed by ammonium acetate
文献类型：期刊论文
| 作者 | Lei, Min2 ; Ma, Lei1; Hu, Lihong2
|
| 刊名 | TETRAHEDRON LETTERS
 |
| 出版日期 | 2011-05-18 |
| 卷号 | 52期号:20页码:2597-2600 |
| 关键词 | Green chemistry Multi-component reaction 4-Hydroxyquinolin-2(1H)-one Aldehyde Malononitrile |
| ISSN号 | 0040-4039 |
| DOI | 10.1016/j.tetlet.2011.03.061 |
| 文献子类 | Article |
| 英文摘要 | A green, efficient, and rapid procedure for the synthesis of 2-amino-3-cyano-1,4,5,6-tetrahydropyrano[3,2-c]quinolin-5-one derivatives has been developed by one-pot condensation of 4-hydroxyquinolin-2(1H)-one, aldehyde, and malononitrile in the presence of ammonium acetate in EtOH. This method has the advantages of operational simplicity, mild reaction conditions, short reaction time, and little environmental impact. (C) 2011 Elsevier Ltd. All rights reserved. |
| WOS关键词 | ONE-POT SYNTHESIS ; SOLVENT-FREE CONDITIONS ; PHOTOCHROMIC PROPERTIES ; PYRAN DERIVATIVES ; NATURAL-PRODUCTS ; IONIC LIQUID ; CONDENSATION ; 4H-PYRANS ; COMPLEXATION ; NAPHTHOPYRAN |
| 资助项目 | Chinese National Science and Technology Major Project 'Key New Drug Creation and Manufacturing Program'[2009ZX09301-001] ; Chinese National Science and Technology Major Project 'Key New Drug Creation and Manufacturing Program'[2009ZX09102-022] ; National Natural Science Foundation of China[21002027] ; National Natural Science Foundation of China[90713046] ; National Natural Science Foundation of China[30772638] ; National Natural Science Foundation of China[30925040] ; CAS Foundation[KSCX2-YW-R-179] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000291332500019 |
| 出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/278525]  |
| 专题 | 上海中药现代化研究中心 |
| 通讯作者 | Ma, Lei |
| 作者单位 | 1.E China Univ Sci & Technol, Sch Pharm, Shanghai 200237, Peoples R China; 2.Shanghai Inst Mat Med, Shanghai Res Ctr Modernizat Tradit Chinese Med, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Lei, Min,Ma, Lei,Hu, Lihong. A green, efficient, and rapid procedure for the synthesis of 2-amino-3-cyano-1,4,5,6-tetrahydropyrano[3,2-c]quinolin-5-one derivatives catalyzed by ammonium acetate[J]. TETRAHEDRON LETTERS,2011,52(20):2597-2600. |
| APA | Lei, Min,Ma, Lei,&Hu, Lihong.(2011).A green, efficient, and rapid procedure for the synthesis of 2-amino-3-cyano-1,4,5,6-tetrahydropyrano[3,2-c]quinolin-5-one derivatives catalyzed by ammonium acetate.TETRAHEDRON LETTERS,52(20),2597-2600. |
| MLA | Lei, Min,et al."A green, efficient, and rapid procedure for the synthesis of 2-amino-3-cyano-1,4,5,6-tetrahydropyrano[3,2-c]quinolin-5-one derivatives catalyzed by ammonium acetate".TETRAHEDRON LETTERS 52.20(2011):2597-2600. |
入库方式： OAI收割
来源：上海药物研究所
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