Thiamine Hydrochloride-Catalyzed One-Pot Synthesis of 1,4-Dihydropyridine Derivatives Under Solvent-Free Conditions
文献类型：期刊论文
| 作者 | Lei, Min2 ; Ma, Lei2; Hu, Lihong1,2
|
| 刊名 | SYNTHETIC COMMUNICATIONS
 |
| 出版日期 | 2011 |
| 卷号 | 41期号:13页码:1969-1976 |
| 关键词 | Aldehydes 1 4-dihydropyridines Hantzsch reaction -keto ester thiamine hydrochloride (VB(1)) |
| ISSN号 | 0039-7911 |
| DOI | 10.1080/00397911.2010.494814 |
| 文献子类 | Article |
| 英文摘要 | [image omitted] An efficient one-pot synthesis of 1,4-dihydropyridines from an aldehyde, -keto ester, and ammonium acetate or formamidine acetate using thiamine hydrochloride (VB1) as the catalyst under solvent-free conditions at ambient temperature is described. All types of aldehydes, including aromatic, aliphatic, and unsaturated aldehydes, give good yields. The catalyst can easily be recovered after completion of the reaction and reused without affecting its activity. |
| WOS关键词 | POLYHYDROQUINOLINE DERIVATIVES ; HANTZSCH 1,4-DIHYDROPYRIDINES ; CALCIUM-CHANNEL ; AMBIENT-TEMPERATURE ; ANTAGONISTS ; CONDENSATION |
| 资助项目 | Chinese National Science and Technology[2009ZX09301-001] ; Chinese National Science and Technology[2009ZX09102] ; Chinese National High-tech RD Program[2007AA02Z147] ; National Natural Science Foundation of China[90713046] ; National Natural Science Foundation of China[30772638] ; National Natural Science Foundation of China[30925040] ; CAS Foundation[KSCX2-YW-R-179] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000290409100011 |
| 出版者 | TAYLOR & FRANCIS INC |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/278680]  |
| 专题 | 上海中药现代化研究中心 |
| 通讯作者 | Ma, Lei |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 200031, Peoples R China 2.E China Univ Sci & Technol, Sch Pharm, Shanghai 200237, Peoples R China; |
| 推荐引用方式 GB/T 7714 | Lei, Min,Ma, Lei,Hu, Lihong. Thiamine Hydrochloride-Catalyzed One-Pot Synthesis of 1,4-Dihydropyridine Derivatives Under Solvent-Free Conditions[J]. SYNTHETIC COMMUNICATIONS,2011,41(13):1969-1976. |
| APA | Lei, Min,Ma, Lei,&Hu, Lihong.(2011).Thiamine Hydrochloride-Catalyzed One-Pot Synthesis of 1,4-Dihydropyridine Derivatives Under Solvent-Free Conditions.SYNTHETIC COMMUNICATIONS,41(13),1969-1976. |
| MLA | Lei, Min,et al."Thiamine Hydrochloride-Catalyzed One-Pot Synthesis of 1,4-Dihydropyridine Derivatives Under Solvent-Free Conditions".SYNTHETIC COMMUNICATIONS 41.13(2011):1969-1976. |
入库方式： OAI收割
来源：上海药物研究所
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