An Approach to 3,6-Disubstituted 2,5-Dioxybenzoquinones via Two Sequential Suzuki Couplings. Three-Step Synthesis of Leucomelone
文献类型：期刊论文
| 作者 | Gan, Xianwen2; Jiang, Wei1; Wang, Wei1,3; Hu, Lihong2,3 |
| 刊名 | ORGANIC LETTERS
 |
| 出版日期 | 2009-02-05 |
| 卷号 | 11期号:3页码:589-592 |
| ISSN号 | 1523-7060 |
| DOI | 10.1021/ol802645f |
| 文献子类 | Article |
| 英文摘要 | Two sequential Suzuki coupling reactions have been developed for efficient synthesis of synthetically and biologically important 3,6-disubstituted 2,5-dioxybenzoquinone architectures in a highly chemoselective controlled manner. The method serves as a key step in the total synthesis of leucomelone in three steps and in 61% overall yield. |
| WOS关键词 | MUSHROOM PAXILLUS-CURTISII ; TNF-ALPHA PRODUCTION ; RADICAL SCAVENGER ; THELEPHORA-VIALIS ; ARYLBORONIC ACIDS ; POTENT INHIBITOR ; EDIBLE MUSHROOM ; PULVINIC ACIDS ; TERPHENYLQUINONES ; DERIVATIVES |
| 资助项目 | National Natural Science Foundation of China[NSFC3057224] ; National Natural Science Foundation of China[30772638] ; Chinese National High-tech RD Program[2007AA02Z147] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000262913500024 |
| 出版者 | AMER CHEMICAL SOC |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/279320]  |
| 专题 | 上海中药现代化研究中心 |
| 通讯作者 | Wang, Wei |
| 作者单位 | 1.Univ New Mexico, Dept Chem & Chem Biol, Albuquerque, NM 87131 USA; 2.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai Res Ctr Modernizat Tradit Chinese Med, Shanghai 210203, Peoples R China; 3.E China Univ Sci & Technol, Sch Pharm, Shanghai 200237, Peoples R China |
| 推荐引用方式 GB/T 7714 | Gan, Xianwen,Jiang, Wei,Wang, Wei,et al. An Approach to 3,6-Disubstituted 2,5-Dioxybenzoquinones via Two Sequential Suzuki Couplings. Three-Step Synthesis of Leucomelone[J]. ORGANIC LETTERS,2009,11(3):589-592. |
| APA | Gan, Xianwen,Jiang, Wei,Wang, Wei,&Hu, Lihong.(2009).An Approach to 3,6-Disubstituted 2,5-Dioxybenzoquinones via Two Sequential Suzuki Couplings. Three-Step Synthesis of Leucomelone.ORGANIC LETTERS,11(3),589-592. |
| MLA | Gan, Xianwen,et al."An Approach to 3,6-Disubstituted 2,5-Dioxybenzoquinones via Two Sequential Suzuki Couplings. Three-Step Synthesis of Leucomelone".ORGANIC LETTERS 11.3(2009):589-592. |
入库方式： OAI收割
来源：上海药物研究所
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