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Screening of AMPK Interacted Proteins by Yeast Two Hybrid System

文献类型：期刊论文

作者Wu Li1; Yang Chenghong1; Deng Sisi2; Zhou Yubo2; Qian Min1; Zang Yi2
刊名Journal of Chinese Biotechnology
出版日期2012
卷号32期号:2页码:1-7
关键词AMPK Yeast two hybrid Protein-protein interaction
ISSN号1671-8135
其他题名应用酵母双杂交系统筛选AMPK相互作用蛋白
文献子类Article
英文摘要Adenosine Monophosphate-activated protein kinase(AMP-activated protein kinase,AMPK),a serine/threonine protein kinase,regulates cellular energy homeostasis.Based on yeast two hybrid assay,63 proteins identified interacted with AMPK beta1 subunit in the human universal cDNA library.Among these proteins,there are 30 enzymes including metabolic enzymes,kinases and SUMO protease,9 transcription factors or their coregulators,5 transport/cargo proteins,4 GTP-binding proteins,3 adaptors and some proteins involved in cell cycle,DNA repair and cell growth and/or maintainance.These results suggested that AMPK may play a key role not only in the metabolism but also in non-metabolism processes in the cellular functions.
资助项目国家重大科学研究计划发育与生殖专项[00000000] ; 上海市公共服务平台资助项目[00000000]
WOS研究方向Biotechnology & Applied Microbiology (provided by Clarivate Analytics)
语种中文
CSCD记录号CSCD:4448158
源URL[http://119.78.100.183/handle/2S10ELR8/267851]  
专题国家新药筛选中心
通讯作者Zang Yi
作者单位1.School of Life Science,East China Normal University, Shanghai 200062, China.;
2.The National Center for Drug Screening,Shanghai Institute of Materia Medica,Chinese Academy of Sciences, Shanghai 201203, China.
推荐引用方式
GB/T 7714		 Wu Li,Yang Chenghong,Deng Sisi,et al. Screening of AMPK Interacted Proteins by Yeast Two Hybrid System[J]. Journal of Chinese Biotechnology,2012,32(2):1-7.
APA Wu Li,Yang Chenghong,Deng Sisi,Zhou Yubo,Qian Min,&Zang Yi.(2012).Screening of AMPK Interacted Proteins by Yeast Two Hybrid System.Journal of Chinese Biotechnology,32(2),1-7.
MLA Wu Li,et al."Screening of AMPK Interacted Proteins by Yeast Two Hybrid System".Journal of Chinese Biotechnology 32.2(2012):1-7.

入库方式： OAI收割

来源：上海药物研究所

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