Modulation of pulmonary fibrosis by renin-angiotensin system
文献类型：期刊论文
| 作者 | Gong Li; Ren Jin
|
| 刊名 | Chinese Journal of Pharmacology and Toxicology
 |
| 出版日期 | 2005 |
| 卷号 | 19期号:5页码:396-400 |
| 关键词 | renin-angiotensin system pulmonary fibrosis |
| ISSN号 | 1000-3002 |
| 其他题名 | 肾素-血管紧张素系统对肺纤维化形成的调节 |
| 文献子类 | Article |
| 英文摘要 | Local renin-angiotensin system (RAS) compo-nents are recognized as regulators of cell growth, cell apoptosis, expression of- inflammatory mediators and fibro-genesis. Activation of a local RAS within the lung could influence the pathogenesis of pulmonary fibrosis via a number of mechanisms. RAS inhibition can reduce cell apoptosis of alveolar epithelial cells and endothelial cells, interfere with the inflammation cascade, and decrease fi-broblast activity during tissue repair process. Better un-derstanding of the multiple actions of local RAS may aid to develop new pharmacologic agents for pulmonary fibro-sis and other fibrotic disorders. |
| WOS研究方向 | General & Internal Medicine (provided by Clarivate Analytics) |
| 语种 | 中文 |
| CSCD记录号 | CSCD:2040657 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/268305]  |
| 专题 | 药物安全性评价中心 |
| 通讯作者 | Ren Jin |
| 作者单位 | State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 201203, China. |
| 推荐引用方式 GB/T 7714 | Gong Li,Ren Jin. Modulation of pulmonary fibrosis by renin-angiotensin system[J]. Chinese Journal of Pharmacology and Toxicology,2005,19(5):396-400. |
| APA | Gong Li,&Ren Jin.(2005).Modulation of pulmonary fibrosis by renin-angiotensin system.Chinese Journal of Pharmacology and Toxicology,19(5),396-400. |
| MLA | Gong Li,et al."Modulation of pulmonary fibrosis by renin-angiotensin system".Chinese Journal of Pharmacology and Toxicology 19.5(2005):396-400. |
入库方式： OAI收割
来源：上海药物研究所
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