BCRP-targeted reverse of multidrug resistance: research progress and drug development
文献类型：期刊论文
| 作者 | Yu Cunzhi; Qi Xinming ; Ren Jin
|
| 刊名 | Chinese Pharmacological Bulletin
 |
| 出版日期 | 2014 |
| 卷号 | 30期号:5页码:615-618 |
| 关键词 | BCRP breast cancer resistance protein (BCRP) tumor multidrug resistance expression regulation subcellular localization energy dependence transport activity inhibition clinical drug strategy drug development |
| ISSN号 | 1001-1978 |
| 其他题名 | 靶向乳腺癌耐药蛋白逆转肿瘤耐药:研究进展与药物开发 |
| 文献子类 | Review |
| 英文摘要 | As an important ABC transporter, breast cancer resistance protein (BCRP) plays an important role in tumor multidrug resistance. Many laboratories are focusing on BCRP to reverse multidrug resistance. We summarize in the paper the research progress on the regulation of BCRP expression, subcellular localization, ATP-dependence, inhibition or modulation of its transport activity and potential clinical treatment strategies in order to provide theoretical support and some new research ideas for the reverse of multidrug resistance in clinic. |
| 资助项目 | 国家自然科学基金资助项目[00000000] ; 科技重大专项单元平台课题[00000000] ; 科技重大专项关键技术课题[00000000] |
| WOS研究方向 | General & Internal Medicine (provided by Clarivate Analytics) |
| 语种 | 中文 |
| CSCD记录号 | CSCD:5130672 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/269338]  |
| 专题 | 药物安全性评价中心 |
| 通讯作者 | Ren Jin |
| 作者单位 | Center for Drug Safety Evaluation and Research, State Key Laboratory of New Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China. |
| 推荐引用方式 GB/T 7714 | Yu Cunzhi,Qi Xinming,Ren Jin. BCRP-targeted reverse of multidrug resistance: research progress and drug development[J]. Chinese Pharmacological Bulletin,2014,30(5):615-618. |
| APA | Yu Cunzhi,Qi Xinming,&Ren Jin.(2014).BCRP-targeted reverse of multidrug resistance: research progress and drug development.Chinese Pharmacological Bulletin,30(5),615-618. |
| MLA | Yu Cunzhi,et al."BCRP-targeted reverse of multidrug resistance: research progress and drug development".Chinese Pharmacological Bulletin 30.5(2014):615-618. |
入库方式： OAI收割
来源：上海药物研究所
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