Allosteric modulators of G-protein coupled receptors
文献类型：期刊论文
| 作者 | Wang Haonan; Yang Dehua ; Wang Mingwei
|
| 刊名 | Chemistry of Life
 |
| 出版日期 | 2013 |
| 卷号 | 33期号:4页码:389-395 |
| 关键词 | G-protein coupled receptor allosteric modulator orthosteric site allosteric site |
| ISSN号 | 1000-1336 |
| 其他题名 | G蛋白偶联受体别构调节剂 |
| 文献子类 | Review |
| 英文摘要 | Allosteric modulators of G-protein coupled receptors are capable of inducing conformational changes that are transmitted to the orthosteric site. They can not only regulate orthosteric ligand binding and/ or its efficacy but also act in manners that are different from the classic drugs, thereby demonstrating many distinct advantages. With deepening of our understanding concerning the actions of allosteric regulation, agents of novel therapeutic mechanisms are expected to be unmasked while implementing the development strategy on allosteric modulators. |
| 资助项目 | 国家科技重大专项[00000000] ; 上海市科学技术委员会基金项目[00000000] |
| WOS研究方向 | Pharmacology & Pharmacy (provided by Clarivate Analytics) |
| 语种 | 中文 |
| CSCD记录号 | CSCD:4929064 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/269372]  |
| 专题 | 国家新药筛选中心 |
| 通讯作者 | Wang Mingwei |
| 作者单位 | The National Center for Drug Screening,Shanghai Institute of Materia Medica,Chinese Academy of Sciences, Shanghai 201203, China. |
| 推荐引用方式 GB/T 7714 | Wang Haonan,Yang Dehua,Wang Mingwei. Allosteric modulators of G-protein coupled receptors[J]. Chemistry of Life,2013,33(4):389-395. |
| APA | Wang Haonan,Yang Dehua,&Wang Mingwei.(2013).Allosteric modulators of G-protein coupled receptors.Chemistry of Life,33(4),389-395. |
| MLA | Wang Haonan,et al."Allosteric modulators of G-protein coupled receptors".Chemistry of Life 33.4(2013):389-395. |
入库方式： OAI收割
来源：上海药物研究所
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