Nondestructive imaging of the internal microstructure of vessels and nerve fibers in rat spinal cord using phase-contrast synchrotron radiation microtomography
文献类型：期刊论文
| 作者 | Hu, Jianzhong3; Li, Ping3; Yin, Xianzhen2; Wu, Tianding3; Cao, Yong3; Yang, Zhiming3; Jiang, Liyuan3; Hu, Shiping3; Lu, Hongbin1 |
| 刊名 | JOURNAL OF SYNCHROTRON RADIATION
 |
| 出版日期 | 2017-03 |
| 卷号 | 24页码:482-489 |
| 关键词 | synchrotron radiation imaging virtual slices three-dimensional microstructure phase-contrast imaging spinal cord |
| ISSN号 | 1600-5775 |
| DOI | 10.1107/S1600577517000121 |
| 文献子类 | Article |
| 英文摘要 | The spinal cord is the primary neurological link between the brain and other parts of the body, but unlike those of the brain, advances in spinal cord imaging have been challenged by the more complicated and inhomogeneous anatomy of the spine. Fortunately with the advancement of high technology, phase-contrast synchrotron radiation microtomography has become widespread in scientific research because of its ability to generate high-quality and high-resolution images. In this study, this method has been employed for nondestructive imaging of the internal microstructure of rat spinal cord. Furthermore, digital virtual slices based on phase-contrast synchrotron radiation were compared with conventional histological sections. The three-dimensional internal microstructure of the intramedullary arteries and nerve fibers was vividly detected within the same spinal cord specimen without the application of a stain or contrast agent or sectioning. With the aid of image post-processing, an optimization of vessel and nerve fiber images was obtained. The findings indicated that phase-contrast synchrotron radiation microtomography is unique in the field of three-dimensional imaging and sets novel standards for pathophysiological investigations in various neurovascular diseases. |
| WOS关键词 | IN-VIVO ; VIRTUAL HISTOLOGY ; MOUSE ; TOMOGRAPHY ; INJURY ; NETWORK ; EMBRYOS ; MRI ; CT |
| 资助项目 | National Natural Science Foundation of China, Beijing, China[81171698] ; National Natural Science Foundation of China, Beijing, China[81301542] ; National Natural Science Foundation of China, Beijing, China[81371956] |
| WOS研究方向 | Instruments & Instrumentation ; Optics ; Physics |
| 语种 | 英语 |
| WOS记录号 | WOS:000395093600015 |
| 出版者 | INT UNION CRYSTALLOGRAPHY |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/272760]  |
| 专题 | 分子影像中心（筹） |
| 通讯作者 | Lu, Hongbin |
| 作者单位 | 1.Cent S Univ, Xiangya Hosp, Dept Sports Med, Res Ctr Sports Med, Changsha 410008, Hunan, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 200135, Peoples R China; 3.Cent S Univ, Xiangya Hosp, Dept Spine Surg, Changsha 410008, Hunan, Peoples R China; |
| 推荐引用方式 GB/T 7714 | Hu, Jianzhong,Li, Ping,Yin, Xianzhen,et al. Nondestructive imaging of the internal microstructure of vessels and nerve fibers in rat spinal cord using phase-contrast synchrotron radiation microtomography[J]. JOURNAL OF SYNCHROTRON RADIATION,2017,24:482-489. |
| APA | Hu, Jianzhong.,Li, Ping.,Yin, Xianzhen.,Wu, Tianding.,Cao, Yong.,...&Lu, Hongbin.(2017).Nondestructive imaging of the internal microstructure of vessels and nerve fibers in rat spinal cord using phase-contrast synchrotron radiation microtomography.JOURNAL OF SYNCHROTRON RADIATION,24,482-489. |
| MLA | Hu, Jianzhong,et al."Nondestructive imaging of the internal microstructure of vessels and nerve fibers in rat spinal cord using phase-contrast synchrotron radiation microtomography".JOURNAL OF SYNCHROTRON RADIATION 24(2017):482-489. |
入库方式： OAI收割
来源：上海药物研究所
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