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A new staurosporine analog from Actinomycetes Streptomyces sp (172614)

文献类型：期刊论文

作者Li, Xiao-Bin2; Tang, Jin-Shan2; Gao, Hao2; Ding, Rong4; Li, Jia1; Hong, Kui3; Yao, Xin-Sheng2,4
刊名JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
出版日期2011
卷号13期号:8页码:765-769
关键词Streptomyces sp. staurosporine analog cytotoxicity HCT 116
ISSN号1028-6020
DOI10.1080/10286020.2011.586342
文献子类Article
英文摘要A new staurosporine analog, 10'-{5 ''-[(methoxycarbonyl) amino]-2 ''-methyl}-phenylaminocarbonylstaurosporine (1), together with staurosporine (2), was obtained from the culture broth of Actinomycetes Streptomyces sp. (172614). Their structures were elucidated by comprehensive spectroscopic analysis including UV, MS, NMR, and CD spectra. Pharmacological experiments revealed that 1 and 2 showed significant cytotoxicity against human colon tumor cell HCT-116.
资助项目Ministry of Science and Technology of China[2009CB522300] ; Ministry of Science and Technology of China[2009ZX09302-004] ; Ministry of Education of China/Fok Ying Tung Education Foundation[121039]
WOS研究方向Plant Sciences ; Chemistry ; Pharmacology & Pharmacy
语种英语
WOS记录号WOS:000294802100013
出版者TAYLOR & FRANCIS LTD
源URL[http://119.78.100.183/handle/2S10ELR8/278656]  
专题国家新药筛选中心
药物安全性评价中心
通讯作者Yao, Xin-Sheng
作者单位1.Chinese Acad Sci, Shanghai Inst Mat Med, Natl Ctr Drug Screening, Shanghai 201203, Peoples R China;
2.Jinan Univ, Coll Pharm, Inst Tradit Chinese Med & Nat Prod, Guangzhou 510632, Guangdong, Peoples R China;
3.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Haikou 571101, Peoples R China
4.Shenyang Pharmaceut Univ, Coll Tradit Chinese Mat Med, Shenyang 110016, Peoples R China;
推荐引用方式
GB/T 7714		 Li, Xiao-Bin,Tang, Jin-Shan,Gao, Hao,et al. A new staurosporine analog from Actinomycetes Streptomyces sp (172614)[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2011,13(8):765-769.
APA Li, Xiao-Bin.,Tang, Jin-Shan.,Gao, Hao.,Ding, Rong.,Li, Jia.,...&Yao, Xin-Sheng.(2011).A new staurosporine analog from Actinomycetes Streptomyces sp (172614).JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,13(8),765-769.
MLA Li, Xiao-Bin,et al."A new staurosporine analog from Actinomycetes Streptomyces sp (172614)".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 13.8(2011):765-769.

入库方式： OAI收割

来源：上海药物研究所

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