Cytotoxic Amide Alkaloids from Piper boehmeriaefolium
文献类型：期刊论文
| 作者 | Tang, Gui-Hua1,2; Chen, Dong-Mei3; Qiu, Bei-Ying3; Sheng, Li3; Wang, Yue-Hu1; Hu, Guang-Wan1; Zhao, Fu-Wei1,2; Ma, Li-Juan4; Wang, Huan5; Huang, Qiao-Qin5 |
| 刊名 | JOURNAL OF NATURAL PRODUCTS
 |
| 出版日期 | 2011-01 |
| 卷号 | 74期号:1页码:45-49 |
| ISSN号 | 0163-3864 |
| DOI | 10.1021/np100606u |
| 文献子类 | Article |
| 英文摘要 | Eight new amide alkaloids (1-8) and 19 known ones were isolated from the whole plant of Piper boehmeriaefolium. Their structures were determined through spectroscopic data analyses. Cytotoxic activity of these amides against human cervical carcinoma HeLa cells was evaluated, and 1-[(9E)-10-(3,4-methylenedioxyphenyl)-9-decenoyl]pyrrolidine (9) exhibited significant inhibitory activity with an IC50 value of 2.7 mu g/mL. |
| WOS关键词 | CONSTITUENTS ; NIGRUM ; IDENTIFICATION ; RETROFRACTUM ; TUBERCULATUM ; ALKAMIDES ; HISPIDUM ; LEAVES ; FRUITS ; LARVAE |
| 资助项目 | National Natural Science Foundation of China[20972166] ; National Natural Science Foundation of China[31070288] ; Ministry of Education of China[B08044] ; Ministry of Education of China[MUC 98503-001006] ; Chinese Academy of Sciences[00000000] |
| WOS研究方向 | Plant Sciences ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000286577800009 |
| 出版者 | AMER CHEMICAL SOC |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/278663]  |
| 专题 | 国家新药筛选中心 药物安全性评价中心 |
| 通讯作者 | Long, Chun-Lin |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, Key Lab Econ Plants & Biotechnol, Kunming 650204, Peoples R China; 2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China; 3.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China; 4.Minzu Univ China, Coll Life & Environm Sci, Beijing 100081, Peoples R China; 5.Yunnan Agr Univ, Kunming 650201, Peoples R China |
| 推荐引用方式 GB/T 7714 | Tang, Gui-Hua,Chen, Dong-Mei,Qiu, Bei-Ying,et al. Cytotoxic Amide Alkaloids from Piper boehmeriaefolium[J]. JOURNAL OF NATURAL PRODUCTS,2011,74(1):45-49. |
| APA | Tang, Gui-Hua.,Chen, Dong-Mei.,Qiu, Bei-Ying.,Sheng, Li.,Wang, Yue-Hu.,...&Li, Jia.(2011).Cytotoxic Amide Alkaloids from Piper boehmeriaefolium.JOURNAL OF NATURAL PRODUCTS,74(1),45-49. |
| MLA | Tang, Gui-Hua,et al."Cytotoxic Amide Alkaloids from Piper boehmeriaefolium".JOURNAL OF NATURAL PRODUCTS 74.1(2011):45-49. |
入库方式： OAI收割
来源：上海药物研究所
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