H-1 and C-13 assignments of two new macrocyclic lactones isolated from Streptomyces sp 211726 and revised assignments of Azalomycins F-3a, F-4a and F-5a
文献类型：期刊论文
| 作者 | Yuan, Ganjun1,2,3; Lin, Haipeng1; Wang, Cheng1; Hong, Kui1,3; Liu, Yue4; Li, Jia4
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| 刊名 | MAGNETIC RESONANCE IN CHEMISTRY
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| 出版日期 | 2011-01 |
| 卷号 | 49期号:1页码:30-37 |
| 关键词 | NMR H-1 NMR C-13 NMR 2D NMR Azalomycin F-4a 2-ethylpentyl ester Azalomycin F-5a 2-ethylpentyl ester Streptomyces sp 211726 macrocyclic lactone |
| ISSN号 | 0749-1581 |
| DOI | 10.1002/mrc.2697 |
| 文献子类 | Article |
| 英文摘要 | Azalomycin F-4a 2-ethylpentyl ester (1) and Azalomycin F-5a 2-ethylpentyl ester (2), two new macrocyclic lactones, along with three known compounds of Azalomycins F-3a (3), F-4a (4) and F-5a (5), were identified from metabolites of Streptomyces sp. 211726 isolated from mangrove rhizosphere soil. The complete H-1 and C-13 assignments of these compounds were achieved by using H-1, C-13, DEPT, HSQC, H-1-H-1 COSY and HMBC spectra, and the relative stereochemistry of 5 was first elucidated on the basis of proton-proton coupling constants, NOESY and IR spectra. Moreover, some errors in the H-1 and C-13 assignments published of 3, 4 and 5 were found and revised. 1 and 2 were active against Candida albicans, and exhibited moderate cyctotoxicity against HCT-116 cell line. Copyright (C) 2010 John Wiley & Sons, Ltd. |
| WOS关键词 | ANTIBIOTICS |
| 资助项目 | National High Technology Development Project (863)[2007AA09Z415] ; National Natural Science Foundation of China[U0633008] |
| WOS研究方向 | Chemistry ; Spectroscopy |
| 语种 | 英语 |
| WOS记录号 | WOS:000285962900006 |
| 出版者 | WILEY-BLACKWELL |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/278664]  |
| 专题 | 国家新药筛选中心 药物安全性评价中心 |
| 通讯作者 | Hong, Kui |
| 作者单位 | 1.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Key Lab Trop Microbial Resources, Haikou 571101, Peoples R China; 2.Hainan Med Coll, Dept Pharm, Haikou 571101, Peoples R China; 3.Hainan Univ, Coll Agr, Haikou 570228, Peoples R China; 4.Chinese Acad Sci, Shanghai Inst Mat Med, Natl Ctr Drug Screening, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yuan, Ganjun,Lin, Haipeng,Wang, Cheng,et al. H-1 and C-13 assignments of two new macrocyclic lactones isolated from Streptomyces sp 211726 and revised assignments of Azalomycins F-3a, F-4a and F-5a[J]. MAGNETIC RESONANCE IN CHEMISTRY,2011,49(1):30-37. |
| APA | Yuan, Ganjun,Lin, Haipeng,Wang, Cheng,Hong, Kui,Liu, Yue,&Li, Jia.(2011).H-1 and C-13 assignments of two new macrocyclic lactones isolated from Streptomyces sp 211726 and revised assignments of Azalomycins F-3a, F-4a and F-5a.MAGNETIC RESONANCE IN CHEMISTRY,49(1),30-37. |
| MLA | Yuan, Ganjun,et al."H-1 and C-13 assignments of two new macrocyclic lactones isolated from Streptomyces sp 211726 and revised assignments of Azalomycins F-3a, F-4a and F-5a".MAGNETIC RESONANCE IN CHEMISTRY 49.1(2011):30-37. |
入库方式： OAI收割
来源：上海药物研究所
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