Deep eutectic solvents functionalized polymers for easily and efficiently promoting biocatalysis
文献类型：期刊论文
| 作者 | Li, Liteng1; Liu, Kaijing1; Xing, Hanli1; Li, Xiaofang1; Zhang, Qiangguo1; Han, Dandan2,3; He, Hongyan4; Yan, Hongyuan2,3; Tang, Baokun1,2,4 |
| 刊名 | JOURNAL OF CATALYSIS
 |
| 出版日期 | 2019-06-01 |
| 卷号 | 374页码:306-319 |
| 关键词 | Deep eutectic solvent Polymer Enzyme Adsorption Hydrolysis |
| ISSN号 | 0021-9517 |
| DOI | 10.1016/j.jcat.2019.05.006 |
| 英文摘要 | Biocompatible and magnetic polymers of poly(vinyl pyrrolidone deep eutectic solvent, VP DES) were investigated to determine whether they could efficiently adsorb L-asparaginase, which is an important enzyme inhibiting the growth of certain tumor cells. A series of poly(VP DES)s were successfully obtained, and that based on VP-malonic acid (VP/MA molar ratio of 1:1) was found to be the best for L-asparaginase adsorption. In addition, L-asparaginase was easily separated with biocompatible poly (VP-MA DES) from Escherichia coli extracts under a magnetic field with a high specific activity toward the hydrolysis of L-asparagine, as determined by the Nessler reaction method. Based on this work, poly(VP-MA DES)s seem ideal carriers via adsorption for the delivery of specific enzyme for the biocatalysis. (C) 2019 Elsevier Inc. All rights reserved. |
| WOS关键词 | MOLECULARLY IMPRINTED POLYMERS ; SELECTIVE RECOGNITION ; L-ASPARAGINASE ; EXTRACTION ; NANOPARTICLES ; COMPOSITE ; POLYMERIZATION ; IMMOBILIZATION ; MICROSPHERES ; NANOSPHERES |
| 资助项目 | Natural Science Foundation of Hebei Province[E2018201155] ; Natural Science Foundation of Hebei Province[B2018201270] ; Open Project Fund of Key Laboratory of Natural Resources of Changbai Mountain & Functional Molecules (Yanbian University), Ministry of Education[NRFM201705] ; Creation and Innovation Program of Hebei Province University Students[201810075085] ; High-level Talents Introduction Program of Hebei University ; National Natural Science Foundation of China[21575033] ; National Natural Science Foundation of China[81803287] |
| WOS研究方向 | Chemistry ; Engineering |
| 语种 | 英语 |
| WOS记录号 | WOS:000483423600032 |
| 出版者 | ACADEMIC PRESS INC ELSEVIER SCIENCE |
| 资助机构 | Natural Science Foundation of Hebei Province ; Open Project Fund of Key Laboratory of Natural Resources of Changbai Mountain & Functional Molecules (Yanbian University), Ministry of Education ; Creation and Innovation Program of Hebei Province University Students ; High-level Talents Introduction Program of Hebei University ; National Natural Science Foundation of China |
| 源URL | [http://ir.ipe.ac.cn/handle/122111/30686]  |
| 专题 | 中国科学院过程工程研究所 |
| 通讯作者 | Yan, Hongyuan; Tang, Baokun |
| 作者单位 | 1.Hebei Univ, Coll Pharmaceut Sci, Key Lab Pharmaceut Qual Control Hebei Prov, Baoding 071002, Peoples R China 2.Hebei Univ, Key Lab Med Chem & Mol Diag, Minist Educ, Baoding 071002, Peoples R China 3.Hebei Univ, Coll Publ Hlth, Baoding 071002, Peoples R China 4.Chinese Acad Sci, Inst Proc Engn, CAS Key Lab Green Proc & Engn, Beijing 010190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Liteng,Liu, Kaijing,Xing, Hanli,et al. Deep eutectic solvents functionalized polymers for easily and efficiently promoting biocatalysis[J]. JOURNAL OF CATALYSIS,2019,374:306-319. |
| APA | Li, Liteng.,Liu, Kaijing.,Xing, Hanli.,Li, Xiaofang.,Zhang, Qiangguo.,...&Tang, Baokun.(2019).Deep eutectic solvents functionalized polymers for easily and efficiently promoting biocatalysis.JOURNAL OF CATALYSIS,374,306-319. |
| MLA | Li, Liteng,et al."Deep eutectic solvents functionalized polymers for easily and efficiently promoting biocatalysis".JOURNAL OF CATALYSIS 374(2019):306-319. |
入库方式： OAI收割
来源：过程工程研究所
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