Insight into the efficiency of oxygen introduced photodynamic therapy (PDT) and deep PDT against cancers with various assembled nanocarriers
文献类型：期刊论文
| 作者 | Zhao, Jie3; Duan, Li4; Wang, Anhe1; Fei, Jinbo3; Li, Junbai2,3 |
| 刊名 | WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY
 |
| 出版日期 | 2019-09-30 |
| 页码 | 20 |
| ISSN号 | 1939-5116 |
| 关键词 | Nanocarriers Photodynamic therapy (PDT) Oxygen introduction Deep PDT Cancers |
| DOI | 10.1002/wnan.1583 |
| 英文摘要 | Photodynamic therapy (PDT) has been used in the treatment of cancers and other benign diseases for several years in clinic. However, the hypoxia of tumors and the penetration limitation of excitation light to tissues can dramatically reduce the efficacy of PDT to cancers. To overcome these drawbacks, various assembled nanocarriers such as nanoparticles, nanocapsules, nanocrystals, and so on were introduced. The assembled nanocarriers have the ability of loading photosensitizers, delivering O-2 into tumors, generating O-2 in situ in tumors, as well as turning near-infrared (NIR) light, X-rays, and chemical energy into ultraviolet or visible light. Therefore, it is easy for the nanocarriers to improve the hypoxia microenvironment or increase the treatment depth of cancers, which will improve the efficiency of PDT to some degree. In recent years, a number of investigations were focused on these subjects. We will summarize the advances of nanocarriers in PDT, especially in O-2 introduction PDT and deep PDT. The perspectives, challenges, and potential in translation of PDT will also be discussed. This article is categorized under: Therapeutic Approaches and Drug Discovery > Emerging Technologies Biology-Inspired Nanomaterials > Lipid-Based Structures Therapeutic Approaches and Drug Discovery > Nanomedicine for Oncologic Disease |
| WOS关键词 | UP-CONVERSION NANOPARTICLES ; NEAR-INFRARED LIGHT ; MESOPOROUS SILICA NANOPARTICLES ; METAL-ORGANIC FRAMEWORKS ; IN-VIVO ; HIGHLY EFFICIENT ; 2-PHOTON ABSORPTION ; INDOCYANINE GREEN ; SINGLET OXYGEN ; GOLD NANORODS |
| 资助项目 | National Nature Science Foundation of China[21433010] ; National Nature Science Foundation of China[21872150] ; National Nature Science Foundation of China[91027045] |
| WOS研究方向 | Science & Technology - Other Topics ; Research & Experimental Medicine |
| 语种 | 英语 |
| 出版者 | WILEY |
| WOS记录号 | WOS:000488163600001 |
| 资助机构 | National Nature Science Foundation of China |
| 源URL | [http://ir.ipe.ac.cn/handle/122111/30866]  |
| 专题 | 中国科学院过程工程研究所 |
| 通讯作者 | Li, Junbai |
| 作者单位 | 1.Chinese Acad Sci, Inst Proc Engn, Natl Key Lab Biochem Engn, Beijing, Peoples R China 2.Univ Chinese Acad Sci, Beijing, Peoples R China 3.Chinese Acad Sci, Inst Chem, BNLMS, CAS Key Lab Colloid Interface & Chem Thermodynam, Beijing 100190, Peoples R China 4.Northwest Inst Nucl Technol, Xian, Shanxi, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhao, Jie,Duan, Li,Wang, Anhe,et al. Insight into the efficiency of oxygen introduced photodynamic therapy (PDT) and deep PDT against cancers with various assembled nanocarriers[J]. WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY,2019:20. |
| APA | Zhao, Jie,Duan, Li,Wang, Anhe,Fei, Jinbo,&Li, Junbai.(2019).Insight into the efficiency of oxygen introduced photodynamic therapy (PDT) and deep PDT against cancers with various assembled nanocarriers.WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY,20. |
| MLA | Zhao, Jie,et al."Insight into the efficiency of oxygen introduced photodynamic therapy (PDT) and deep PDT against cancers with various assembled nanocarriers".WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY (2019):20. |
入库方式： OAI收割
来源：过程工程研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。