中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
comparativeevaluationofabiomimiccollagenhydroxyapatitetricaleiumphosphatescaffoldinalveolarridgepreservationwithbioosscollagen

文献类型:期刊论文

作者Wang Tong4; Li Qing4; Zhang Guifeng3; Zhou Gang2; Yu Xin2; Zhang Jing2; Wang Xiumei1; Tang Zhihui4
刊名frontiersofmaterialsscience
出版日期2016
卷号10期号:2页码:122
ISSN号2095-025X
英文摘要Bone scaffolds are critical in current implant and periodontal regeneration approaches. In this study, we prepared a novel composite type-l collagen and hydroxyapatite (HA)/β-tricaleium phosphate (TCP) scaffold (CHTS) by incorporating type-1 collagen and bovine calcined bone granules, prepared as a mixture of 50% HA and 50% TCP, by freeze drying. We then characterized the CHTS and determined its cytotoxic effects. Additionally, ridge preservation experiments were carried out to evaluate the clinical effects of the CHTS. The results demonstrated that the composite scaffolds had good surface morphology and no cytotoxicity. Additionally, an in vivo experiment in an animal model showed that the CHTS performed equally as well as Bio-Oss Collagen, a widely used bone graft in ridge preservation. These findings revealed that the CHTS, which contained natural constituents of bone, could be used as a scaffold for bone regeneration and clinical use.
语种英语
源URL[http://ir.ipe.ac.cn/handle/122111/36015]  
专题中国科学院过程工程研究所
作者单位1.清华大学
2.北京航空航天大学
3.中国科学院过程工程研究所
4.北京大学
推荐引用方式
GB/T 7714
Wang Tong,Li Qing,Zhang Guifeng,et al. comparativeevaluationofabiomimiccollagenhydroxyapatitetricaleiumphosphatescaffoldinalveolarridgepreservationwithbioosscollagen[J]. frontiersofmaterialsscience,2016,10(2):122.
APA Wang Tong.,Li Qing.,Zhang Guifeng.,Zhou Gang.,Yu Xin.,...&Tang Zhihui.(2016).comparativeevaluationofabiomimiccollagenhydroxyapatitetricaleiumphosphatescaffoldinalveolarridgepreservationwithbioosscollagen.frontiersofmaterialsscience,10(2),122.
MLA Wang Tong,et al."comparativeevaluationofabiomimiccollagenhydroxyapatitetricaleiumphosphatescaffoldinalveolarridgepreservationwithbioosscollagen".frontiersofmaterialsscience 10.2(2016):122.

入库方式: OAI收割

来源:过程工程研究所

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