comparativeevaluationofabiomimiccollagenhydroxyapatitetricaleiumphosphatescaffoldinalveolarridgepreservationwithbioosscollagen
文献类型:期刊论文
作者 | Wang Tong4; Li Qing4; Zhang Guifeng3; Zhou Gang2; Yu Xin2; Zhang Jing2; Wang Xiumei1; Tang Zhihui4 |
刊名 | frontiersofmaterialsscience
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出版日期 | 2016 |
卷号 | 10期号:2页码:122 |
ISSN号 | 2095-025X |
英文摘要 | Bone scaffolds are critical in current implant and periodontal regeneration approaches. In this study, we prepared a novel composite type-l collagen and hydroxyapatite (HA)/β-tricaleium phosphate (TCP) scaffold (CHTS) by incorporating type-1 collagen and bovine calcined bone granules, prepared as a mixture of 50% HA and 50% TCP, by freeze drying. We then characterized the CHTS and determined its cytotoxic effects. Additionally, ridge preservation experiments were carried out to evaluate the clinical effects of the CHTS. The results demonstrated that the composite scaffolds had good surface morphology and no cytotoxicity. Additionally, an in vivo experiment in an animal model showed that the CHTS performed equally as well as Bio-Oss Collagen, a widely used bone graft in ridge preservation. These findings revealed that the CHTS, which contained natural constituents of bone, could be used as a scaffold for bone regeneration and clinical use. |
语种 | 英语 |
源URL | [http://ir.ipe.ac.cn/handle/122111/36015] ![]() |
专题 | 中国科学院过程工程研究所 |
作者单位 | 1.清华大学 2.北京航空航天大学 3.中国科学院过程工程研究所 4.北京大学 |
推荐引用方式 GB/T 7714 | Wang Tong,Li Qing,Zhang Guifeng,et al. comparativeevaluationofabiomimiccollagenhydroxyapatitetricaleiumphosphatescaffoldinalveolarridgepreservationwithbioosscollagen[J]. frontiersofmaterialsscience,2016,10(2):122. |
APA | Wang Tong.,Li Qing.,Zhang Guifeng.,Zhou Gang.,Yu Xin.,...&Tang Zhihui.(2016).comparativeevaluationofabiomimiccollagenhydroxyapatitetricaleiumphosphatescaffoldinalveolarridgepreservationwithbioosscollagen.frontiersofmaterialsscience,10(2),122. |
MLA | Wang Tong,et al."comparativeevaluationofabiomimiccollagenhydroxyapatitetricaleiumphosphatescaffoldinalveolarridgepreservationwithbioosscollagen".frontiersofmaterialsscience 10.2(2016):122. |
入库方式: OAI收割
来源:过程工程研究所
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